Molecular Genetic Analysis Applied to Evolution, Ecology, and Systemic Biology: An Extended Laboratory Course

我们提出了一个本科师资增强项目，在接下来的两年里，每年提供为期12天的分子遗传学和进化生物学实验室短期课程，每年1月提供为期4天的后续课程，并提供持续的技术和物质支持。在设计和开发我们提议的本科师资加强项目时，采用了一个非常成功的建立形式，该形式是从之前的十个国家肖托夸课程演变而来的。每年将从社区大学、4年制文理大学、综合大学、研究型大学的教师中选拔22名教师。参与者将通过讲座和演示学习分子生物学的基础知识，并进行一系列实验，以培养PCR扩增，限制性内切酶分析和各种凝胶分离技术的技能。在由社区大学和四年制大学的教师组成的4-5人的研究小组中，参与者将调查“专题”研究项目。演讲人将讨论他们在原核动物、脊椎动物、无脊椎动物和植物系统方面的研究，以及他们在分子技术方面的应用。教师将把他们所学到的分子技术应用到各自机构的本科实验课程中。训练有素的教师将获得这些技术所提供的非凡能力，以获取地球上任何分类群的自然种群的基因组，从而在他们自己的机构中创建独特的实验室课程。旧金山州立大学的教师和教学支持技术员将在夏季课程结束后为参与者提供支持，将分子技术和分析结合到本科教学中。参与者还将培养在他们的研究中使用分子技术的技能和信心。讲习班将用于编制实验室单元和练习，供中小学教育使用。

We propose an Undergraduate Faculty Enhancement project that will provide for each of the next two years, an intense twelve-day laboratory short course in Molecular Genetics & Evolutionary Biology in the summer with a 4-day follow-up session each January, and on-going technical and material support. A highly successful established format that evolved from ten prior national Chautauqua courses was used in the design and development of our proposed Undergraduate Faculty Enhancement project. Twenty-two faculty will be selected each year from a national applicant pool comprised of faculty from community colleges, 4-year liberal arts colleges and universities, comprehensive universities, and research universities. Participants will learn the fundamentals of molecular biology through the presentation of lectures and demonstrations, and they will also conduct a series of experiments to develop skill in PCR amplification, restriction enzyme analysis, and various gel separation techniques. In research groups of 4-5 composed of a mix faculty from community colleges and four-year institutions, the participants will investigate "thematic" research projects. Seminar speakers will discuss their research on procaryote, vertebrate, invertebrate, and plant systems, and their application of molecular techniques. Faculty will implement the molecular techniques that they learn by adapting the exercises from the course into undergraduate laboratory courses at their respective institutions. Trained faculty will have gained the extraordinary capabilities afforded by these techniques to access the genomes of natural populations from any taxa on earth and thus create unique laboratory curricula at their own institutions. The SFSU faculty and Instructional Support Technician will support participants after the summer course in the incorporation of molecular techniques and analysis in undergraduate instruction. Participants will also develop skill and confidence with molecular techn iques to use in their research. The workshop will be used to develop laboratory modules and exercises for use in primary and secondary education.