Signal Transduction Training Group

9602259该奖项重申了对1991年首次成立的爱荷华州立大学信号转导研究培训小组的支持。在第二个奖项的任期内，国家科学基金的支持将逐步取消；预计在此期间将获得其他资金来源。这个13人的教职员工团队由来自不同学科背景的优秀高级和初级研究人员组成，但他们在细胞内和细胞外信号转导方面有着共同的兴趣。在最初的一年，续展奖项将为研究生和博士后实习生提供与上一届奖项水平类似的津贴，并与机构资金相结合，将显著增加资助夏季研究项目的本科生数量。并将支付学员研究的部分费用。此外，资金还将用于吸引其他研究和学术机构的杰出研究人员到校园举行研讨会和座谈会。细胞内和细胞间的信号转导是所有类型细胞的基础，对细胞的正常发育和功能起着至关重要的作用。信号转导的例子可能包括与神经系统的发育和功能有关的细胞-细胞相互作用，以及细胞外信号影响单个细胞的新陈代谢、基因表达或结构的暂时或永久性变化的分子机制。通常，对信号转导的研究针对从原子到生物体的多种细胞组织水平中的任何一种。参加这个培训小组的教员使用各种生物物理学和分子生物学技术研究各种生物体。通过整合他们在这些不同领域的研究计划和培训活动，该小组促进了智力和实验方法的交叉培养，这应该会为教师和S的学生提供一种极好的体验。***

9602259 This award renews support for a Research Training Group in Signal Transduction at Iowa State University first established in 1991. During the term of this second award , NSF support will be phased out; it is expected that other sources of funding will be secured during this period. The 13 member faculty group is a mixture of outstanding senior and junior investigators who come from a variety of disciplinary backgrounds, but share a common interest in intra- and extracellular signal transduction. In its initial year, the renewal award will provide stipends for graduate students and postdoctoral trainees at levels similar to the previous award and, in combination with institutional funds will significantly increase the number of undergraduate students sponsored for a summer research program. and will defray part of the cost of the trainees' research. In addition, funds will be used to bring outstanding investigators from other research and academic institutions to the campus for seminars and symposia. Signal transduction within and between cells is fundamental to all types of cells and plays a crucial role in normal cell development and function. Examples of signal transduction might include the cell-cell interactions involved in development and function of the nervous system, and the molecular mechanisms by which extracellular signals effect temporary or permanent changes in the metabolism, gene expression or structure of individual cells. Typically, studies of signal transduction are directed at any of a number of levels of cell organization, from the atomic to the organismal. The faculty participating in this training group study a variety of organisms using a variety of biophyisical and molecular biological techniques. By integrating their research programs and training activities in these various areas, the group promotes a cross fertilization of intellectual and experimental approaches that should provide a superb experience for faculty and s tudents alike. ***