CONFERENCE: Symposium on Subtypes of Muscarinic Receptors; Vienna, VA, November 12-15, 1996

会议：毒蕈碱受体亚型研讨会；

• 批准号: 9603590
• 负责人: Ruth Levine
• 金额: $ 1万
• 依托单位: Trustees of Boston University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-10-15 至 1997-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9603590&HistoricalAwards=false
• 关键词: CONFERENCE; Symposium; Subtypes; Muscarinic; Receptors

9603590 Levin The functional contacts between nerve cells are called synapses, and the biochemical compounds that carry signals between the cells at the synapse are called neurotransmitters. The transmitter molecules are captured on the surface of the cell membrane of the target cell by molecules called receptors. Classes of transmitters, like particular amino acids, or particular catecholamine compounds, were known to have particular receptor types that triggered particular responses in the post-synaptic cell. More recently, subtypes of receptor molecules have been found, often with different chemical binding affinities, molecular arrangement, and coupling mechanisms. This symposium covers recent advances at the molecular level in understanding the subtypes of the particular receptors called muscarinic receptors, which modulate the responses of nerve and muscle cells to a widespread neurotransmitter called acetylcholine. Support is to help cover some travel costs young investigators in the field to be able to attend and deliver their own research results at this meeting. This support will have an impact on fostering the career development of young neuroscientists, and the symposium presentations will have an impact on muscle and cardiovascular research as well as neuroscience.

[603590]列文神经细胞之间的功能性接触被称为突触，在突触上细胞之间传递信号的生化化合物被称为神经递质。发射器分子被称为受体的分子捕获在靶细胞的细胞膜表面。各类递质，如特定的氨基酸，或特定的儿茶酚胺化合物，已知有特定的受体类型，在突触后细胞中触发特定的反应。最近，受体分子的亚型被发现，通常具有不同的化学结合亲和力，分子排列和偶联机制。本次研讨会涵盖了在分子水平上理解特定受体毒蕈碱受体亚型的最新进展，毒蕈碱受体调节神经和肌肉细胞对广泛存在的神经递质乙酰胆碱的反应。支持是帮助支付该领域的年轻研究人员能够参加会议并在会议上发表自己的研究成果的一些旅费。这种支持将对培养年轻神经科学家的职业发展产生影响，研讨会的演讲将对肌肉和心血管研究以及神经科学产生影响。