RUI: Swimming in Rainbow Trout: Ontogeny and Muscle Function

RUI：虹鳟鱼游泳：个体发育和肌肉功能

• 批准号: 9604140
• 负责人: David Coughlin
• 金额: $ 10.45万
• 依托单位: Widener University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2000-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9604140&HistoricalAwards=false
• 关键词: RUI; Swimming; Rainbow; Trout; Ontogeny

9604140 Coughlin Fish provide an elegant system for the study of muscle function. Variations in the location and usage of the different muscle fiber types (slow, intermediate and fast) of fish permit evaluation of how each muscle type contributes to locomotion. Rainbow trout, Oncorhynchus mykiss, show a number of interesting characteristics of muscle function during steady or sustained swimming (i.e. swimming that employs the slow, aerobic muscle fibers only). Dr. Coughlin will explore how distinct patterns of body curvature and electrical activation in the muscle of swimming trout affect muscle function and locomotion. Also, through comparison of the discrete life history stages observed in trout, such as the parr and smolt stages, the PI will examine how developmental changes in body shape and muscle kinetics effect swimming performance. Lastly, through hormone manipulation, rainbow trout development will be manipulated to allow comparisons of swimming at the different life history stages with control for natural differences in size at each stage. The study of fish swimming increases the understanding of muscle function in all vertebrates. While this study will focus on aerobic muscle function in swimming fish, it has implications for our understanding of aerobic muscle function in other systems, especially other cyclically active muscle such as bird flight muscle and the power generating muscle of mammalian limbs.

小行星9604140 鱼类为研究肌肉功能提供了一个极好的系统。 鱼的不同肌纤维类型（慢、中、快）的位置和用途的变化允许评估每种肌肉类型如何对运动做出贡献。 虹鳟鱼在稳定或持续的游泳过程中（即只使用缓慢的有氧肌肉纤维的游泳）显示出许多有趣的肌肉功能特征。 Coughlin博士将探讨不同的身体弯曲模式和电激活的肌肉游泳鳟鱼影响肌肉功能和运动。 此外，通过比较在鳟鱼中观察到的离散生活史阶段，如幼鱼和小鲑鱼阶段，PI将研究体形和肌肉动力学的发育变化如何影响游泳性能。 最后，通过激素的操纵，虹鳟鱼的发育将被操纵，以允许在不同的生活史阶段的游泳与控制在每个阶段的大小的自然差异的比较。 鱼类游泳的研究增加了对所有脊椎动物肌肉功能的理解。 虽然这项研究将集中在游泳鱼类的有氧肌肉功能，但它对我们理解其他系统中的有氧肌肉功能有影响，特别是其他周期性活动的肌肉，如鸟类飞行肌肉和哺乳动物四肢的发电肌肉。