Purchase of Cryogenic Equipment and EDS System Upgrade
Purchase of Cryogenic Equipment and EDS System Upgrade
批准号:
9604767
负责人:
Nina Fedoroff
金额:
$13.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-07-01 至 1999-06-30
中文摘要
纽约城市学院的生物学家正在申请相应的资金,以购买一台透射电子显微镜(TEM)。新的TEM将取代26年前购买的Phillips 300。在新设备的帮助下,研究领域相当广泛,涵盖神经生物学、分子发育遗传学、免疫生物学、原生动物学、分子系统学、内细胞生物学和进化等领域。更具体地说,以下项目将得到援助:1)有孔虫内含硅藻共生体的吞噬体噬菌体加工;2)有孔虫的核运动和系统学;3)浮游硅藻的分子系统学;4)胸腺哺育细胞的细胞表面表型;5)胸腺细胞和胸腺哺育细胞的接触;6)果蝇复眼的分子和遗传学分析;7)非洲爪蛙胚胎和变态神经系统轴突发育和连接专一性的分子机制;8)研究生长因子和神经递质在信号级联中的作用,视网膜通过信号级联调节巩膜的生长,当巩膜倾斜时,可能会导致近视。
英文摘要
Biologists at the City College of New York are requesting matching funds to purchase a transmission electron microscope (TEM). The new TEM will replace a Phillips 300 purchase 26 years ago. The research aided by the new equipment is quite broad in aspect, covering fields such as Neurobiology, Molecular Developmental Genetics, Immunobiology, Protistology, Molecular Systematics, Endocytobiology, and Evolution. More specifically the following projects will be aided: 1) Phagosome- phagolysosomal processing in diatom-bearing endosymbioses in foraminifera; 2) Karyokinesis and systematics of foraminifera; 3) Molecular systematics of planktonic diatoms; 4) Cell surface phenotypes of thymic nurse cells; 5) Contact between thymocytes and thymic nurse cells; 6) Molecular and genetic analysis of the Drosophila compound eye; 7) Molecular mechanisms underlying axonal development and connection specificity in the embryonic and metamorphosing nervous system of the frog Xenopus laevis; and 8) Studies of growth factors and neurotransmitters involved in the signal cascade by means of which the retina modulates growth of the sclera which, when awry, can lead to myopia.
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