Purchase of Cryogenic Equipment and EDS System Upgrade

低温设备采购及EDS系统升级

• 批准号: 9604767
• 负责人: Nina Fedoroff
• 金额: $ 13万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9604767&HistoricalAwards=false
• 关键词: Purchase; Cryogenic; Equipment; EDS; System

Biologists at the City College of New York are requesting matching funds to purchase a transmission electron microscope (TEM). The new TEM will replace a Phillips 300 purchase 26 years ago. The research aided by the new equipment is quite broad in aspect, covering fields such as Neurobiology, Molecular Developmental Genetics, Immunobiology, Protistology, Molecular Systematics, Endocytobiology, and Evolution. More specifically the following projects will be aided: 1) Phagosome- phagolysosomal processing in diatom-bearing endosymbioses in foraminifera; 2) Karyokinesis and systematics of foraminifera; 3) Molecular systematics of planktonic diatoms; 4) Cell surface phenotypes of thymic nurse cells; 5) Contact between thymocytes and thymic nurse cells; 6) Molecular and genetic analysis of the Drosophila compound eye; 7) Molecular mechanisms underlying axonal development and connection specificity in the embryonic and metamorphosing nervous system of the frog Xenopus laevis; and 8) Studies of growth factors and neurotransmitters involved in the signal cascade by means of which the retina modulates growth of the sclera which, when awry, can lead to myopia.

纽约城市学院的生物学家正在申请配套资金， 透射电子显微镜（TEM）。新的TEM将取代26年前购买的菲利普斯300。 新设备辅助的研究领域相当广泛，涵盖神经生物学、分子发育遗传学、免疫生物学、原生生物学、分子系统学、内细胞生物学和进化等领域。 更具体地说，以下项目将得到资助：1）吞噬体-有孔虫中含磷内共生体的吞噬溶酶体加工; 2） 有孔虫的核分裂与系统学; 3）分子生物学 浮游硅藻的分类学; 4）胸腺滋养细胞的细胞表面表型; 5）胸腺细胞和胸腺滋养细胞之间的接触; 6）果蝇复眼的分子和遗传分析; 7）非洲爪蟾胚胎和变态神经系统中轴突发育和连接特异性的分子机制;和8）对参与信号级联的生长因子和神经递质的研究，视网膜通过该信号级联调节巩膜的生长，当巩膜歪斜时，巩膜的生长可导致近视。