Speciation and Dynamics of the Peroxidase-Oxidase Oscillator

在化学部物理化学计划的这个项目中，伊利诺伊大学厄巴纳分校化学系的Alexander Scheeline将使用还原剂、氧气作为氧化剂以及亚甲蓝和2，4-二氯苯酚等辅因子来研究辣根过氧化物酶振荡器。最近的工作使人们对这一系统有了半定量的理解。在新的研究方案中，将进行新的实验，以充分阐明这种振荡反应的机理，并能够寻找其他具有生物学意义的化学振荡器。生物化学振荡器，如本项目中研究的那些，对解开生物钟的机制很有兴趣，生物钟是重要的细胞传输过程的基础，尽管在这种情况下也涉及膜。

In this project in the Physical Chemistry Program of the Chemistry Division, Alexander Scheeline of the Department of Chemistry of the University of Illinois, Urbana will study the horseradish peroxidase oscillator using a reducing agent, oxygen as the oxidant, and cofactors such as methylene blue and 2,4-dichlorophenol. Recent work has led to semiquantitative understanding of this system. In the new research proposal new experiments will be conducted to elucidate fully the mechanism of this oscillating reaction and to be able to search for other biologically interesting chemical oscillators. Biochemical oscillators such as those studied in this project are of interest to unravel the mechanism of biological clocks, which are at the basis of important cellular transmission processes, although in that case also a membrane is involved.