SGER: Pheromonal Induction of Estrus and Ovulation in a Marsupial

SGER：有袋动物发情和排卵的信息素诱导

• 批准号: 9616588
• 负责人: John Harder
• 金额: $ 2.9万
• 依托单位: Ohio State University Research Foundation -DO NOT USE
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-15 至 1999-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9616588&HistoricalAwards=false
• 关键词: SGER; Pheromonal; Induction; Estrus; Ovulation

The majority of species of animals have tightly regulated intrinsic reproductive cycles that are governed by such things as the time of the year or the availability of food. However, in some species reproductive function is governed by non-verbal physical cues, such as chemical attractants or pheromones. These chemicals provide information about the reproductive status of potential mates and may trigger reproductive cyclicity in some species. Dr. John Harder is investigating the reproductive, hormonal and neurobiological consequences of pheromone exposure in a model system completely dependent on chemical signaling. These exciting investigations will advance comparative reproductive biology and provide a unique model for the study of chemical activation on neuronal substrates. In addition, these investigations will have a significant impact on our understanding of the diversity of reproductive strategies used in wild animals and may facilitate the application of that understanding to the preservation of species in the wild and in captivity.

大多数动物都有严格控制的内在繁殖周期，这是由诸如一年中的时间或食物的可用性等因素决定的。然而，在一些物种中，生殖功能是由非语言的物理线索控制的，如化学引诱剂或信息素。这些化学物质提供了潜在配偶生殖状态的信息，并可能引发某些物种的生殖周期。约翰·哈德博士正在研究一个完全依赖化学信号的模型系统中信息素暴露对生殖、激素和神经生物学的影响。这些令人兴奋的研究将推动比较生殖生物学的发展，并为研究神经元基质上的化学激活提供一个独特的模型。此外，这些调查将对我们对野生动物生殖策略多样性的理解产生重大影响，并可能促进将这种理解应用于野生和圈养物种的保护。