STTR Phase II: A Reagentless Fiber-Optic Chemiluminescence Continuous Flow Chlorine Analyzer

STTR 第二阶段：无试剂光纤化学发光连续流氯分析仪

• 批准号: 9626942
• 负责人: James Akse
• 金额: $ 35万
• 依托单位: Umpqua Research Company
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-15 至 1998-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9626942&HistoricalAwards=false
• 关键词: STTR; Phase; II; Reagentless; Fiber

*** 9626942 Akse This Small Business Technology Transfer Phase II project will result in the design, fabrication, and testing of an innovative chemiluminescence (CL) based prototype analyzer capable of continuous chlorine monitoring in water. This innovative new technology combines the intrinsic selectivity and sensitivity of CL with the reproducibility and ease of operation afforded by the use of solid phase modules for control of the pH, luminol concentration, and as a means to calibrate the analyzer. Solid phase beds eliminate the need for reagent preparation, and can be quickly and easily exchanged after long periods of operation (30 days). Monochloramine, the most common interference in colorimetric analysis for chlorine, produces no CL response in the chlorine analyzer. Operation conditions, component hardware, solid phase bed design, and CL detection efficiency will be refined based on performance and commercial potential. Methods will be developed for quantitation of total chlorine and reagentless calibration. A prototype will be built and tested on real water samples forming the basis for commercialization of the technology. Such an instrument will permit precise control of chlorination processes reducing the health risks caused by the formation and release of chlorinated by-products associated with over-chlorination, particularly in drinking water. Current analytical instruments are poorly suited to this task due to interferences, unstable reagents, time dependent responses, operator dependent results, poor reproducibility, and expense. The CL analyzer will meet the need for a sensitive, accurate, highly selective, and inexpensive instrument that is easy to use with a minimum of operator intervention. ***

* 9626942 Akse该小型企业技术转让二期项目将设计、制造和测试一种创新的基于化学发光（CL）的原型分析仪，该分析仪能够连续监测水中的氯。这种创新的新技术结合了CL的固有选择性和灵敏度，以及使用固相模块控制pH值、鲁米诺浓度和校准分析仪所提供的重现性和操作简便性。固相床不需要试剂制备，并且可以在长时间运行（30天）后快速轻松地更换。一氯胺是氯比色分析中最常见的干扰物，在氯分析仪中不产生CL响应。操作条件、组件硬件、固相床设计和CL检测效率将根据性能和商业潜力进行改进。将开发用于总氯定量和无试剂校准的方法。将建造一个原型，并在真实的水样上进行测试，为该技术的商业化奠定基础。 这一文书将允许对氯化过程进行精确控制，从而减少与过度氯化有关的氯化副产品的形成和释放所造成的健康风险，特别是在饮用水中。由于干扰、不稳定的试剂、依赖于时间的响应、依赖于操作者的结果、差的再现性和费用，当前的分析仪器不太适合于该任务。CL分析仪将满足对灵敏、准确、高选择性和廉价仪器的需求，该仪器易于使用，操作人员干预最少。 ***