Postdoctoral Research Fellowships in Chemistry
Postdoctoral Research Fellowships in Chemistry
批准号:
9626981
负责人:
Virginia Cornish
金额:
$8.0万
依托单位:
依托单位国家:
美国
项目类别:
Fellowship Award
财政年份:
1996
资助国家:
美国
项目状态:
已结题
起止时间:
1996-08-01 至 1999-07-31
中文摘要
Virginia W.康沃尔语已被授予NSF博士后研究 化学研究金。 康沃尔语博士获得博士学位, 加州大学伯克利分校的监督下, Peter G.教授舒尔茨 康沃尔语博士将继续研究在 马萨诸塞州理工学院赞助教授 Robert T.绍尔 博士后研究考察了N的重要性- 和稳定α-螺旋的C-帽残基。 这项工作利用遗传 选择以分离在N-和N-端具有特定残基的蛋白质, C帽位置,以及X射线晶体学和核磁共振 共振光谱来表征的三维结构, 蛋白质 了解如何设计遗传 选择,使得除了用新的蛋白质工程化之外, 催化性能,一个我使用的选择,以了解 成功催化的必要条件。 博士后研究奖学金在化学计划被视为 一项重要的基础设施计划,旨在扩大知识 新博士的经验和吸引他们进入有意义的职业生涯, 当代化学研究与教学
英文摘要
Dr. Virginia W. Cornish has been awarded an NSF Postdoctoral Research Fellowship in Chemistry. Dr. Cornish received the doctoral degree from the University of California at Berkeley under the supervision of Professor Peter G. Schultz. Dr. Cornish will continue research at the Massachusetts Institute of Technology under the sponsorship of Professor Robert T. Sauer. The postdoctoral research examines the importance of N- and C-cap residues in stabilizing alpha-helices. The work uses genetic selections to isolate proteins with particular residues in the N- and C-cap positions, as well as x-ray crystallography and nuclear magnetic resonance spectroscopy to characterize the three-dimensional structure of the proteins. Understanding is gained into how to design genetic selections so that in addition to engineering proteins with novel catalytic properties, one my use the selections to learn about the requirement for successful catalysis. The Postdoctoral Research Fellowships in Chemistry Program is viewed as an important infrastructural program designed to broaden the knowledge and experience of new Ph. D.s and attract them into meaningful careers in contemporary chemical research and teaching.
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