Investigation into High Throughput Planar Chromatographic Identification and Quantitations of Antibiotics Using Infrared & UV -- Visible Focal Plane Arrays

利用红外对抗生素进行高通量平面色谱鉴定和定量的研究

• 批准号: 9703581
• 负责人: M. Bonner Denton
• 金额: $ 30.4万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 2000-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9703581&HistoricalAwards=false
• 关键词: Investigation; into; Throughput; Planar; Chromatographic

This award has base support from the Analytical and Surface Chemistry Program of the Division of Chemistry and equipment support from the Office of Multidisciplinary Activities. Prof. M. Bonner Denton of the University of Arizona will investigate the use of infrared (IR) and ultraviolet (UV)approaches to qualitative and quantitative measurements of analytes separated using high performance techniques on thin layer plates. State-of-the-art near-infrared imaging camera technology will be used along with silicon charge-coupled devices for the UV region. Compounds to be studied include a number of antibiotics which will demonstrate the utility of the instrumentation in the area of pharmaceuticals, an industry which is a potential major user of the technology to be developed. State-of-the-art imaging technology will be used to detect and measure quantitatively the compounds separated chromatographically on thin-layer plates. Many samples can be done in parallel. The technology to be developed has the potential to impact very positively on analysis in the pharmaceutical and clinical areas of the health industries and on other manufacturers of chemicals.

该奖项得到了分析和表面化学 化学和设备支持司的方案 多学科活动办公室。 Prof. M.邦纳丹顿 亚利桑那大学将研究红外线（IR）的使用， 定性和定量测量的紫外（UV）方法 使用高性能技术在薄层上分离分析物 板. 最先进的近红外成像相机技术将在 与硅电荷耦合器件一起沿着用于UV区域。 待研究的化合物包括一些抗生素， 演示仪器在以下领域的实用性： 制药业是一个潜在的主要用户， 技术有待开发。 最先进的成像技术将用于探测和测量 用薄层色谱法定量分离化合物 板. 许多样品可以并行完成。 这项技术 发展有可能对分析产生非常积极的影响， 医疗行业的制药和临床领域以及其他 化学品制造商。