Oxidations of Organosulfur Compounds with Molecular Oxygen

在有机动力学项目和数学与物理科学理事会多学科活动办公室的支持下，怀俄明大学化学系的爱德华·l·克莱南教授研究了有机硫化合物与分子氧的氧化。克莱南教授研究了二烷基硫化物与单线态氧的反应，其中观察到物理猝灭和化学反应，并通过观察活性中间体（如O， s -亚砜基亚硫酸盐和硫过亚砜）阐明了它们的机制。对硫代烷和1,3-二硫代烷的光氧化反应也进行了探讨，重点是氢过氧磺酰化物的形成和反应。为了研究环境对有机硫化物氧化的基本影响并开发新的合成方法，克莱南教授研究了1,3-二硫烷的电子转移氧化和沸石微环境中硫化物的分子氧化。含硫有机化合物及其氧化在各种各样的生物、大气和工业过程中都是相当重要的问题。怀俄明大学化学系的爱德华·l·克莱南教授在有机动力学项目和数学与物理科学理事会多学科活动办公室的支持下，研究含硫分子与氧的反应。通过分析这些反应的产物和在生成这些产物的过程中形成的中间化合物，克莱南教授揭示了导致这些反应形成的基本分子事件。除了提供对这种氧化反应的更一般的理解之外，这些研究还导致开发新的机械工具来探索光辅助氧化反应，并发现新的有用的氧化环境和合成重要材料的新方法。

With the support of the Organic Dynamics Program and the Office of Multidisciplinary Activities of the Mathematical and Physical Sciences Directorate, Professor Edward L. Clennan, of the Department of Chemistry at the University of Wyoming, studies the oxidation of organosulfur compounds with molecular oxygen. Professor Clennan examines the reactions of dialkylsulfides with singlet oxygen, in which both physical quenching and chemical reaction are observed, elucidating their mechanisms by observing reactive intermediates such as O,S-sulfenyl sulfinates and thiopersulfoxides. The photooxidations of thiolanes and 1,3-dithianes are also explored, focusing on the formation and reactions of hydroperoxy sulfonium ylides. In order both to investigate the fundamental influence of environment on organic sulfide oxidations and to develop new synthetic methods, Professor Clennan examines the electron transfer oxidation of 1,3-dithianes and the molecular oxidation of sulfides in zeolite microenvironments. Sulfur-containing organic compounds and their oxidation are matters of considerable importance in a wide variety of biological, atmospheric, and industrial processes. Professor Edward L. Clennan, of the Department of Chemistry at the University of Wyoming, with the support of the Organic Dynamics Program and the Office of Multidisciplinary Activities of the Mathematical and Physical Sciences Directorate, studies the reactions of sulfur-containing molecules with oxygen. Through analysis of the products of these reactions and of the intermediate compounds formed en route to these products, Professor Clennan sheds light on the fundamental molecular events responsible for their formation. In addition to the provision of a more general understanding of such oxidation reactions, these studies are leading to the development of new mechanistic tools to explore light-assisted oxidation reactions and the discovery of new and useful oxidizing environments and new methods for the synthesis of important materials.