Unsaturated, Multifunctional Transition Metal Complexes

该奖项在无机，生物无机和有机化学 该计划为Kenneth G博士提供持续的支持。考尔顿 化学系，印第安纳州大学，合成与反应 不饱和有机金属化合物的研究。 理论工作将 与Odile Eisenstein博士合作， 法国蒙彼利埃大学。 研究的目的是 确定具有几种不同性质的化合物的反应性模式 连接到同一金属原子上的功能配体。 化合物 合成的化合物将含有配体的混合物，例如氢化物，卤化物， 烷基和卡宾。 各种配体的相对反应性将是 直接和复杂的反应，如烷基迁移， 在同一分子中的分子内还原消除将是 监测。 多功能金属络合物还可以递送超过 一个官能团连接到另一个分子上。 目标化合物将是 选择它们是因为它们具有亲核或氧化的能力 低温反应。 研究这些条件下的反应性 提高了识别初级反应产物的可能性， 使反应的选择性最大化。 热力学参数为 测定 待研究的具体反应包括还原反应。 从羰基锇中消除苯， 16-电子物种形成14电子化合物，以及 三氟甲基配体以形成二氟甲基配体。 一系列有机金属化合物的不寻常的反应将是 研究，包括C-H和C-F键的活化和反应性， 配位不饱和化合物。 这种反应是 重要的是获得一个基本的了解行为的同质 催化剂的

This award in the Inorganic, Bioinorganic, and Organometallic Chemistry Program provides continued support to Dr. Kenneth G. Caulton of the Chemistry Department, Indiana University, for synthesis and reaction studies of unsaturated organometallic compounds. Theoretical work will be carried out in collaboration with Dr. Odile Eisenstein of the Universite de Montpellier, France. The goal of the research is to determine reactivity patterns for compounds having several different functional ligands attached to the same metal atom. The compounds synthesized will contain a mixture of ligands such as hydride, halide, alkyl, and carbene. Relative reactivity of various ligands will be determined directly and complex reactions such as alkyl migration and intramolecular reduction elimination in the same molecule will be monitored. Multifunctional metal complexes may also deliver more than one functional group to another molecule. The target compounds will be selected because of their ability to undergo nucleophilic or oxidation reactions at low temperature. Studying reactivity under these conditions improves the possibility of identifying primary reaction products and maximizes the selectivity of reactions. Thermodynamic parameters will be determined. Specific reactions to be investigated include reductive elimination of benzene from osmium carbonyls, removal of halide from 16-electron species to form 14-electron compounds, and reaction of trifluoromethyl ligands to form difluoromethyl ligands. Unusual reactions of a wide range of organometallic compounds will be studied, including C-H and C-F bond activation and reactivity of coordinatively unsaturated compounds. Reactions of this kind are important to obtaining a basic understanding the behavior of homogeneous catalysts.