Integrating NMR Spectroscopy into the Chemistry Curriculum

将核磁共振波谱学纳入化学课程

• 批准号: 9750847
• 负责人: Holly Gaede
• 金额: $ 10万
• 依托单位: Ursinus College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 1999-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9750847&HistoricalAwards=false
• 关键词: Integrating; NMR; Spectroscopy; into; Chemistry

The use of nuclear magnetic resonance (NMR) spectroscopy to study molecular structure and dynamics is now an essential element of an effective undergraduate chemistry education. Students without access to a modern NMR spectrometer cannot gain experience in multinuclear, Fourier transform, and multidimensional NMR. Moreover, even with access to a modern instrument, students all too often learn only about structural elucidation with NMR spectroscopy in Organic Chemistry and never about NMR as a tool for studying dynamics. In this project, NMR spectroscopy is implemented vertically throughout the curriculum. The new spectrometer is incorporated into nearly every chemistry laboratory beginning in the first year with Organic Chemistry, where students familiarize themselves with the instrument and learn basic spectral interpretation. As students progress to Analytical, Physical, and Advanced Inorganic courses, the sophistication of the experiments and the number of parameters the student controls are increased. By the time a student participates in senior research, he or she has the skills to design a two-dimensional experiment without assistance. The spectrometer is used to reinforce concepts taught in the classroom, including stereochemistry, fluxionality, Fourier transform, equilibria, thermodynamics, and kinetics. An important aim of the project is to provide students with a perspective of the broad utility of NMR spectroscopy. In addition, the research program benefits from the extended capabilities of the spectrometer, and more of it can result in publication. The curriculum is also affected as new courses are added and multinuclear and solid-state experiments are developed and disseminated. Finally, students are better prepared for graduate school and industry. *

利用核磁共振（NMR）波谱学来研究分子结构和动力学现在是一个有效的本科化学教育的基本要素。没有现代核磁共振光谱仪的学生无法获得多核、傅里叶变换和多维核磁共振的经验。此外，即使有了现代仪器，学生们在有机化学中经常只学到用核磁共振波谱分析结构，而从来没有把核磁共振作为研究动力学的工具。在这个项目中，核磁共振波谱在整个课程中垂直实施。从有机化学的第一年开始，几乎每个化学实验室都配备了新的光谱仪，学生们在这里熟悉仪器并学习基本的光谱解释。随着学生进入分析、物理和高级无机课程，实验的复杂性和学生控制的参数数量增加。当学生参与高级研究时，他或她已经具备了在没有帮助的情况下设计二维实验的技能。光谱仪用于强化课堂上教授的概念，包括立体化学、流动性、傅立叶变换、平衡、热力学和动力学。该项目的一个重要目的是让学生了解核磁共振波谱的广泛应用。此外，该研究计划受益于光谱仪的扩展功能，并且更多的研究成果可以发表。随着新课程的增加和多核实验和固态实验的发展和传播，课程也受到影响。最后，学生们为研究生院和行业做好了更好的准备。*