SBIR Phase I: A Fast Field Portable Gas Phase Explosives Detector

SBIR 第一阶段：快速现场便携式气相爆炸物探测器

• 批准号: 9761106
• 负责人: John Bowen
• 金额: $ 9.98万
• 依托单位: Bowen Scientific Products, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-01-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9761106&HistoricalAwards=false
• 关键词: SBIR; Phase; Fast; Field; Portable

This Small Business Innovation Research Phase I project proposes to establish proof concept for a sensitive, rapid response, portable biosensor that can be utilized in the detection of undetonated explosives in air. A prototype instrument will be derived from the results of this research based on the detection of the gas phase antibody-antigen reaction between immobilized TNT antibody and vapor phase TNT using Surface Plasmon Resonance Spectroscopy (SPRS). The research involves two studies: ionization of the specific antibody onto a specially prepared gold surface and exploration of the capabilities of SPRS to detect the antibody-antigen reaction. The studies will also assess the limits of delectability, speed, and reproducibility of detection. A need exists for fast, reliable, field portable detectors for undetonated explosives. Applications can range from the detection of luggage bombs at airports to the detection of land mines and other explosives for the military. This award is supported by the Small Business Innovation Research Program and the Experimental Program to Stimulate Competitive Research (EPSCoR).

这个小型企业创新研究第一阶段项目建议为一种灵敏、快速反应的便携式生物传感器建立证明概念，该传感器可用于检测空气中未引爆的爆炸物。利用表面等离子体共振光谱(SPRS)检测固定化TNT抗体与气相TNT之间的气相抗体-抗原反应，并根据本研究的结果设计出一台样机。这项研究包括两项研究：将特定抗体电离到专门准备的金表面上，并探索SPRS检测抗体-抗原反应的能力。这些研究还将评估检测的可味性、速度和重复性的限度。存在对快速、可靠、野外便携式未引爆爆炸物探测器的需求。应用范围从机场的行李炸弹探测到军方的地雷和其他爆炸物。该奖项由小企业创新研究计划和激励竞争研究的实验计划(EPSCoR)支持。