Gordon Research Conference on Nitric Oxide in Biochemistry and Biology to be held February of 1999 at the Harbor Towne Resort in Ventura, California

戈登生物化学和生物学中一氧化氮研究会议将于 1999 年 2 月在加利福尼亚州文图拉的 Harbour Towne Resort 举行

• 批准号: 9809928
• 负责人: Owen Griffith
• 金额: $ 0.49万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-15 至 1999-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9809928&HistoricalAwards=false
• 关键词: Gordon; Research; Conference; Nitric; Oxide

9809928 Griffith It has been known for decades that nitric oxide is a product of combustion and a major component of air pollution. Nonetheless, the effects of nitric oxide on biological systems received only modest attention. Interest in nitric oxide escalated in 1986 with the discovery that nitric oxide is produced endogenously in mammals including man; in the subsequent 12 years there has been an explosion of research and knowledge in this area. Because nitric oxide is a small, freely diffusible, free radical gas it is a most unusual biological mediator. Understanding the biochemistry and biology of nitric oxide requires not only the usual disciplines of enzymology, physiology and pharmacology, but also a sophisticated appreciation of nitric oxide chemistry. It is particularly important that scientists with these diverse interests and areas of expertise meet together periodically to share questions, insights, and experimental approaches. The third biennial Gordon Research Conference on Nitric Oxide in Biochemistry and Biology, which is supported by this grant, meets this need. The conference will be held in February, 1999, in Ventura, California, and will bring together for a five-day meeting investigators from across the country and around the world. In traditional Gordon Conference style, participation will be limited to 125 scientists. Topics to be covered at the conference include the biological chemistry of nitric oxide, the enzymology of nitric oxide synthesis, the regulation of nitric oxide metabolism in intact cells, the molecular mechanisms of nitric oxide cytotoxicity, oxidative stress and nitric oxide production, signal transduction mechanisms involving nitric oxide, and metabolism of nitric oxide in bacteria and fungi. NSF funds will be used to facilitate the attendance of beginning investigators, postdoctoral fellows, and graduate students by reimbursing their travel and registration expenses.

9809928 Griffith几十年来，人们已经知道一氧化氮是燃烧的产物，也是空气污染的主要成分。尽管如此，一氧化氮对生物系统的影响只得到了适度的关注。1986年，随着一氧化氮在包括人类在内的哺乳动物中内源性产生的发现，对一氧化氮的兴趣逐渐增加;在随后的12年里，这一领域的研究和知识出现了爆炸式增长。因为一氧化氮是一种小的、可自由扩散的自由基气体，所以它是一种最不寻常的生物介质。了解一氧化氮的生物化学和生物学不仅需要酶学，生理学和药理学的常规学科，而且还需要对一氧化氮化学的复杂理解。尤其重要的是，具有不同兴趣和专业领域的科学家定期聚会，分享问题，见解和实验方法。 第三届两年一度的戈登研究会议一氧化氮在生物化学和生物学，这是由该补助金支持，满足这一需要。会议将于1999年2月在加州的文图拉举行，来自全国和世界各地的调查人员将参加为期五天的会议。按照传统的戈登会议风格，与会者将限于125名科学家。会议的主题包括一氧化氮的生物化学，一氧化氮合成的酶学，一氧化氮在完整细胞中代谢的调节，一氧化氮细胞毒性的分子机制，氧化应激和一氧化氮的产生，涉及一氧化氮的信号转导机制，以及一氧化氮在细菌和真菌中的代谢。NSF的资金将用于促进新的研究人员，博士后研究员和研究生的出席，报销他们的旅行和注册费用。