Integrating Authentic Research into Undergraduate Sci. Majors' and Non-Majors' Curricula: Automated DNA Sequencing and Genotyping at a Consortium of Three Tacoma-Area Universities

将真实的研究融入本科科学。

• 批准号: 9851614
• 负责人: Peter Wimberger
• 金额: $ 5.02万
• 依托单位: University of Puget Sound
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9851614&HistoricalAwards=false
• 关键词: Integrating; Authentic; Research; into; Undergraduate

A consortium of the three primarily undergraduate universities in Tacoma, Washington is introducing fluorescent automated sequencing and genotyping to their students. The sequencer/genotyper allows introduction of labs that engage majors in the collection and analysis of original data. Although the sequencer is used most heavily for junior/senior level labs (212 students/year) and in senior thesis or capstone projects (20 40 students/year), it is also used to enhance the undergraduate experience at all levels. Freshmen and students in the non-majors biology courses (596 students/year) are introduced to the techniques of molecular biology through a population study of local salmon species. Both majors and non-majors in classes that emphasize the connection between science and society (190 students/year) are genotyping themselves or sequencing a portion of their own DNA, an exercise that helps them to understand the technology and how it is used. In the upper-level electives, each college is implementing focused research projects that will allows students to design and carry out original research during the course. Most of these research projects are directly related to Pacific Northwest organisms or ecological problems. The data generated is useful to government agencies and community groups in the area. Research students and principal investigators at all three institutions also present papers and posters at regional and national meetings; thus disseminating the results of this project to the scientific and educational communities.

位于华盛顿州塔科马市的三所主要本科大学组成的联盟正在向学生介绍荧光自动测序和基因分型。测序/基因型允许引入实验室，从事原始数据的收集和分析。虽然测序器主要用于初级/高级水平的实验室（212名学生/年）和高级论文或顶点项目（20 - 40名学生/年），但它也用于提高各级本科生的经验。通过对当地鲑鱼种群的研究，向新生和非专业生物学课程（596名学生/年）的学生介绍分子生物学技术。在强调科学与社会之间联系的课程中（每年190名学生），无论是主修专业还是非主修专业的学生，都要对自己的部分DNA进行基因分型或测序，这是一项帮助他们理解技术及其使用方法的练习。在高级选修课中，每个学院都在实施重点研究项目，允许学生在课程中设计和开展原创性研究。这些研究项目大多与太平洋西北地区的生物或生态问题直接相关。所产生的数据对该地区的政府机构和社区团体很有用。所有三个机构的研究学生和主要调查人员也在区域和国家会议上提交论文和海报；从而将该项目的成果传播给科学界和教育界。