Development Of A New High Resolution Ion Mobility Spectrometer For Chemistry Research

这份来自化学研究仪器和设施（CRIF）项目的合同将使华盛顿州立大学化学系的Herbert Hill能够开发一种高分辨率离子迁移率光谱仪，该光谱仪带有电喷雾电离源和四极杆质量分析仪，用于识别迁移率分离离子。电喷雾/离子迁移率/质谱法（EIMMS）将基于它们的碰撞截面和质量实现大分子离子的高分辨率分离和鉴定。离子迁移率光谱法是一种非常有效的分离大分子多构象的方法。EIMMS是一种有价值的定量和定性工具，用于分析测定环境，生物和工业混合物中的许多极性和非挥发性化合物。

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program will enable Herbert Hill in the Chemistry Department at Washington State University to develop a high-resolution ion mobility spectrometer with an electrospray ionization source and a quadrupole mass analyzer for the identification of mobility separated ions. Electrospray/ion mobility/mass spectrometry (EIMMS) will enable the high-resolution separation and identification of macromolecular ions based on their collision cross section and their mass. Ion mobility spectrometry is an extremely powerful separation method for multiple conformations of macromolecules. EIMMS is a valuable quantitative and qualitative tool for the analytical determination of many polar and non-volatile compounds in environmental, biological and industrial mixtures.