SFB 670: Cell-Autonomous Immunity

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The response of an organism to pathogens proceeds in several steps, beginning with the natural barriers, e.g., the membrane of a plant cell or the skin of the mammalia, followed by the elements of the innate immunity, which enable an early defence reaction. The initial processing of the pathogen non-self antigens in somatic cells as well as the spatiotemporally concerted defence reaction including various elements of the innate immunity normally set the course for a coordinated and well-balanced adaptive immune response.