STC: The Nanobiotechnology Center

STC：纳米生物技术中心

• 批准号: 9876771
• 负责人: Harold Craighead
• 金额: $ 2373.82万
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9876771&HistoricalAwards=false
• 关键词: STC; Nanobiotechnology; Center

9876771CraigheadThis award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.***

9876771 Craighead该奖项是一个科学和技术中心致力于纳米生物技术的新兴领域，涉及纳米微加工和生物系统的密切合成。 纳米生物技术中心（NBTC）的特点是高度跨学科，密切合作之间的生命科学家，物理科学家，和工程师从康奈尔大学，普林斯顿大学，俄勒冈州健康科学大学，和纽约州卫生部的沃兹沃斯中心。 NBTC的整合愿景是，纳米生物技术将成为对生物系统功能的新见解的起源，并导致新类别的纳米和微加工设备和系统的设计。 生物系统提出了一个特殊的挑战，因为生物应用的材料和化学系统的多样性远远超过集成电路工业中的硅基技术。 适用于生物材料的新的制造工艺将需要对有机和无机系统之间的界面的知识有实质性的扩展。 在从分子到细胞尺度的小尺度上结构化材料和图案化表面化学的能力是NBTC研究的基础技术。 纳米纤维还可以用于形成新的分析探针，用于以前所未有的空间分辨率和灵敏度询问生物系统。 促进材料，工艺和工具进步的三个统一技术平台是NBTC研究计划的基础和支持：纳米生物技术分子;将分子和细胞附着到基底上的图案化表面的新方法;以及纳米生物技术的传感器和设备。 新开发的制造能力也将通过康奈尔纳米工厂的广泛资源提供，这是NSF国家纳米工厂用户网络的一个网站。 NBTC将成为参与机构教育任务的一个组成部分。 NBTC教师将开发一个新的基础研究生课程，在纳米生物技术具有纳米纤维与生物应用的重点。 从工程或生物学背景进入NBTC的研究生将通过从事重要的补充课程工作在其他领域进行交叉培训。 参加NBTC将使他们具备学科深度和跨学科理解，成为这一新兴领域的下一代领导者。 将建立一个具有强大指导结构的本科生研究经验计划，重点是招募妇女和代表性不足的少数民族参加该计划。 计划开展教育推广活动，以激发各年龄段学生的兴趣。 与伊萨卡岛科学中心合作的一项活动是为博物馆展示纳米尺寸主题的巡回展览。 国家和联邦实验室以及工业和其他合作伙伴将参与NBTC的各个方面，例如接待实习生，参加研讨会和科学家交流。 将强调与工业分支机构建立伙伴关系，以加强知识转让以及学生和博士后培训。这个特殊的STC奖由工程局与生物科学，数学和物理科学以及教育和人力资源局协调管理。