A Database of General Biomolecular Information for Education and Research
用于教育和研究的一般生物分子信息数据库
基本信息
- 批准号:9904796
- 负责人:
- 金额:$ 40.87万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:1999
- 资助国家:美国
- 起止时间:1999-09-01 至 2002-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This project will define, implement and evaluate a resource that will bridge the boundary between the scientific literature and web-accessible databases of primary scientific data. The goals are: 1) to create a prototype that integrates general biomolecular information with supporting data found in the Protein Data Bank (PDB), 2) to evaluate this prototype as an extensible model by which textual and graphical information in general may be linked to primary scientific data, providing a model for use in other resources and journals.The proposed database will contain general information on a wide range of biological molecules, including information on their structure, function, and relevance to human life. The entire resource will be authored at a non-technical level, providing quick, easily-comprehensible background material for use by researchers, educators, students, and the general public. The database will allow a PDB user, when approaching a new protein, to obtain a general introduction to the structural and functional features of the molecule, from which the user may gain a deeper understanding of the context of the molecules within the PDB. Linkages to the primary data will allow users, empowered by this introductory material, to explore topics of interest in more detail.The database will be composed of two types of information. First, the database will contain information on individual molecules, describing the structure and function of the molecule and its relevance of each molecule to human life. Links to the PDB and to other appropriate databases will suggest files that would be most appropriate for further study. Second, the database will include information on topics of interest to human life, health, and industry. These entries will refer the user to relevant molecules and to related topics.The resource will be built upon XML (extendable markup language), allowing creation of a flexible, extensible resource. Authoring of new pages will be fast and straightforward, and an XML-based WWW interface will allow new pages to be immediately incorporated into the resource. A simple set of tags inserted into the textual material will identify topics. The WWW interface to the resource will allow searching of all avallable pages within the resource, and will use the XML tags to create links dynamically, linking appropriate pages from the entire database at the time of the search. In this way, new pages may be added at any time, and obsolete pages may be discarded without the need to resolve linkage problems.
该项目将界定、实施和评价一种资源,它将在科学文献和可在网上查阅的原始科学数据数据库之间架起一座桥梁。目标是:1)创建一个将一般生物分子信息与在蛋白质数据库(PDB)中找到的支持数据相结合的原型,2)将该原型评估为可扩展模型,通过该模型,一般的文本和图形信息可以与原始科学数据相关联,提供用于其他资源和期刊的模型。包括关于其结构、功能和与人类生活相关性的信息。整个资源将在非技术层面上编写,提供快速,易于理解的背景材料,供研究人员,教育工作者,学生和公众使用。该数据库将允许PDB用户在接近新蛋白质时获得对分子的结构和功能特征的一般介绍,由此用户可以更深入地理解PDB内分子的背景。与原始数据的联系将使用户在这一介绍性材料的帮助下能够更详细地探讨感兴趣的专题。首先,数据库将包含单个分子的信息,描述分子的结构和功能以及每个分子与人类生命的相关性。与PDB和其他适当数据库的链接将建议最适合进一步研究的文件。第二,数据库将包括与人类生活、健康和工业有关的主题的信息。这些条目将为用户提供相关分子和相关主题的参考。资源将基于XML(可扩展标记语言)构建,允许创建灵活的可扩展资源。新页面的创作将是快速和直接的,基于XML的WWW界面将允许新页面立即合并到资源中。插入文本材料的一组简单的标签将识别主题。到资源的WWW接口将允许搜索资源中的所有可用页面,并将使用XML标记动态创建链接,在搜索时链接整个数据库中的适当页面。通过这种方式,可以随时添加新页面,并且可以丢弃过时的页面,而无需解决链接问题。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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