Dissertation Research: Roots, Genes, and Sciences: Re-Visioning Sickle Cell Knowledge in Dakar

论文研究：根源、基因和科学：在达喀尔重新审视镰状细胞知识

• 批准号: 9906636
• 负责人: Paul Rabinow
• 金额: $ 1.2万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-15 至 2000-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9906636&HistoricalAwards=false
• 关键词: Dissertation; Research; Roots; Genes; Sciences

The proposed dissertation research documents the flow of sickle cell disease knowledge between Paris and Dakar. The conditions and constraints of sickle cell anemia in Senegal have prompted French-trained physicians at the Hopital Albert Royer in the Fann area of Dakar to question the universality of sickle cell patient care and treatment protocols as these have been established in the United States and France. Sickle cell disease in Atlantic Africa is known to correspond with a specific genetic variant (the Senegalese haplotype) which may be responsible for a less severe form of this disease. This project takes seriously a dialectic between culture and biology, by tracing the ways in which biological difference, geography and cultural values contribute to the modification of scientific and medical knowledge. Through interpretive social science methods based on interviews and participant-observation, the investigator will analyze the dynamic processes that allow for rethinking approaches to sickle cell care in Senegal and elsewhere.

拟议的论文研究记录了巴黎和达喀尔之间镰状细胞病知识的流动。塞内加尔镰状细胞性贫血的条件和限制促使在达喀尔Fann地区Albert Royer医院受过法国培训的医生质疑在美国和法国建立的镰状细胞患者护理和治疗方案的普遍性。已知大西洋非洲的镰状细胞病与一种特定的遗传变异（塞内加尔单倍型）相对应，这种变异可能导致这种疾病的一种不太严重的形式。该项目通过追踪生物差异、地理和文化价值如何促进科学和医学知识的修改，认真看待文化与生物学之间的辩证关系。通过基于访谈和参与者观察的解释性社会科学方法，研究者将分析塞内加尔和其他地方允许重新思考镰状细胞护理方法的动态过程。