Improvement of Undergraduate Laboratory Experiences with UV-Vis Spectrophotometry

紫外-可见分光光度法本科实验室经验的改进

• 批准号: 9952641
• 负责人: Massimo Bezoari
• 金额: $ 1.05万
• 依托单位: Huntingdon College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-15 至 2001-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9952641&HistoricalAwards=false
• 关键词: Improvement; Undergraduate; Laboratory; Experiences; UV

Chemistry (12) The Department of Chemistry is augmenting the current one-semester lecture-only Biochemistry course to a two-semester course with laboratories in both semesters. The long-term goal is to develop a Biochemistry major at the College. Experiments from the educational literature are being extended and modified in order to introduce students to spectroscopic analysis in the basic physical science core courses. A UV-Vis spectrophotometer is being used in experiments relating to nucleic acid structure analysis, protein analysis, and kinetics. The project is strengthening the chemistry curriculum by adding to the use of modern technology in lecture and laboratory courses for science and non-science majors. Students are engaged in learning about molecular structure by conducting analyses relating to electronic transitions and molecular orbitals, and studying the effects of structural features on these analyses. Hands-on use of the instrument begins in the Organic laboratory with the characterization of chlorophylls extracted from plants. Students study environmental and biochemical applications, such as thermal denaturation of DNA, and multicomponent analysis in the Analytical/Environmental Chemistry course. Novel forensic science applications are being developed. The instrument is supporting the growing interest of our students in undergraduate research projects, establishing further connections in learning how science is done and making them better prepared for graduate school and industrial employment in chemistry. The project will influence an outside audience with dissemination of project results through presentations, publications in international chemistry research and chemistry education journals, the World-Wide Web, and interactions with educators at scientific meetings. The success of the project will be determined by the establishment of the two-semester Biochemistry course with laboratories, student course evaluations, the number of majors taking undergraduate research projects, formal presentations, publications, and surveys.PROJECT DATA FORM AND PROJECT SUMMARYThe Department of Chemistry plans to augment the current one-semester lecture-only Biochemistry course to a two-semester course with labs in both semesters. The long-term goal is to develop a Biochemistry major at the College. The acquisition of a UV-Vis spectrophotometer will permit inclusion of experiments relating to nucleic acid structure analysis, protein analysis, and kinetics. The project will strengthen the chemistry curriculum by adding to the use of modem technology in lecture and laboratory courses for science and non-science majors. Students will be engaged in learning about molecular structure by conducting analyses relating to electronic transitions and molecular orbitals, and studying the effects of structural features on these analyses. Hands-on use of the instrument will begin in the Organic laboratory with the characterization of chlorophylls extracted from plants. Students will study environmental and biochemical applications, such as thermal denaturation of DNA, and multicomponent analysis in the Analytical/Environmental Chemistry course. Novel forensic science applications will be developed. The instrument will increase the growing interest of our students in undergraduate research projects, establishing further connections in learning how science is done and making them better prepared for graduate school and industrial employment in chemistry. The project will influence an outside audience with dissemination of project results through presentations, publications in international chemistry research and chemistry education journals, the World-Wide Web, and interactions with educators at scientific meetings. The success of the project will be determined by the establishment of the two-semester Biochemistry course with laboratories, student course evaluations, the number of majors taking undergraduate research projects, formal presentations, publications, and surveys.

化学（12）化学系将目前只讲授一学期的生物化学课程改为两个学期的课程，两个学期都有实验。长期目标是在学院发展生物化学专业。为了在基础物理科学核心课程中向学生介绍光谱分析，对教育文献中的实验进行了扩展和修改。紫外可见分光光度计被用于核酸结构分析、蛋白质分析和动力学的实验中。该项目通过在科学和非科学专业的讲座和实验课程中增加使用现代技术来加强化学课程。学生通过分析电子跃迁和分子轨道来了解分子结构，并研究结构特征对这些分析的影响。仪器的实际使用开始在有机实验室从植物中提取叶绿素的特性。学生在分析/环境化学课程中学习环境和生化应用，如DNA的热变性和多组分分析。新的法医学应用正在开发中。该仪器正在支持我们的学生对本科研究项目日益增长的兴趣，建立进一步的联系，以了解科学是如何完成的，并使他们更好地准备研究生院和工业就业的化学。该项目将通过报告、国际化学研究和化学教育期刊的出版物、万维网以及在科学会议上与教育工作者的互动，传播项目结果，从而影响外部受众。该计划的成功与否将取决于两学期生物化学实验课程的设置、学生课程评价、本科生研究课题的专业数量、正式报告、出版物、调查等。项目资料表格及项目摘要化学系计划将目前只讲授一学期的生物化学课程增加为两学期的课程，两个学期都有实验。长期目标是在学院发展生物化学专业。获得紫外可见分光光度计将允许包含与核酸结构分析，蛋白质分析和动力学相关的实验。该项目将通过在理科生和非理科生的讲座和实验课程中加入现代技术来加强化学课程。学生将通过分析电子跃迁和分子轨道来学习分子结构，并研究结构特征对这些分析的影响。仪器的实际使用将在有机实验室开始，从植物中提取叶绿素的特性。学生将在分析/环境化学课程中学习环境和生化应用，如DNA的热变性和多组分分析。将开发新的法医学应用。该仪器将增加学生对本科研究项目日益增长的兴趣，在学习科学如何完成方面建立进一步的联系，并使他们为化学研究生院和工业就业做好更好的准备。该项目将通过报告、国际化学研究和化学教育期刊的出版物、万维网以及在科学会议上与教育工作者的互动，传播项目结果，从而影响外部受众。该计划的成功与否将取决于两学期生物化学实验课程的设置、学生课程评价、本科生研究课题的专业数量、正式报告、出版物、调查等。