POWRE: Biodegradable Micro and Nanopatterned Polymer Substrates for Nerve Regeneration

本提案的目标是制造具有微米和纳米尺度图案的聚合物表面，用于引导雪旺细胞的神经再生。这些凹槽将在可生物降解的聚（乳酸-羟基乙酸）表面上产生，使用光刻技术获得微米级凹槽，原子力显微镜获得纳米图案。这一建议将使PI拓宽她的研究兴趣到细胞/生物材料的相互作用，并促进生物材料课程的发展

The goal of this proposal is to fabricate polymer surfaces with micron and nanometer scale patterns for guided nerve regeneration from Schwann cells. The grooves will be produced on biodegradable poly- (lactic-co-glycolic acid) surfaces using photolithography for the micron scale grooves and atomic force microscopy for the nanopatterns. This proposal will enable the PI to broaden her research interests into cell/biomaterial interactions and facilitate the development of a course on biomaterials