Mechanistic Chemistry of Transition Metal Oxygen and Oxo Complexes

过渡金属氧和氧配合物的机理化学

• 批准号: 9982004
• 负责人: James Espenson
• 金额: $ 31.5万
• 依托单位: Iowa State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-01 至 2004-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9982004&HistoricalAwards=false
• 关键词: Mechanistic; Chemistry; Transition; Metal; Oxygen

Dr. James Espenson and Dr. Andreja Bakac of Iowa State University are supported by the Inorganic, Bioinorganic, and Organometallic Chemistry program for a program of research dealing with the mechanisms of processes in which a single oxygen atom (or equivalent fragment) is transferred from one atom to another during chemical processes. Several classes of such reactions will be studied. One of these is the catalysis of reductions of perchlorate ion by anions such as molybdate. The reactivity of nitric oxide (NO) with superoxo metal complexes and metal ions and related reactions will be explored. The research will also extend to the transfer of fragments that resemble oxygen (such as sulfur) and groups such as NR and CR2 that are isoelectronic with oxygen.Many chemical reactions that are of major practical significance involve movement of an oxygen atom originally attached to one molecule to another location, where that atom is attached to a quite different molecule. Other chemical entities (sulfur atoms, small organic fragments) participate in chemical changes that are quite similar, in important respects, to these simple atom-transfer processes. Drs. Espenson and Bakac will investigate several systems that hold promise of greatly extending understanding of the fundamental principles that govern atom-transfer reactions. At least two of these systems are also of major and immediate practical interest. Contamination by perchlorate ion is an emerging environmental hazard in many parts of the United States. Reduction by atom transfer is the best way to destroy perchlorate ion. Nitric oxide (NO) is known to be an important signaling agent within biological organisms. The functioning of this species is greatly influenced by atom transfer processes. Fundamental understanding sought in this research will bear on these and other important processes.

爱荷华州立大学的詹姆斯·埃斯佩森（James Espenson）博士和安德烈亚·巴卡克（Andreja Bakac）博士得到了无机，生物有机和有机金属化学计划的支持，该计划涉及处理过程机制的研究计划，其中在化学过程中将单个氧原子（或等效片段）从一个原子转移到另一个原子。 将研究几类此类反应。其中之一是诸如molybdate之类的阴离子的高氯酸盐离子减少的催化。将探索一氧化氮（NO）与超氧金属络合物和金属离子以及相关反应的反应性。这项研究还将扩展到类似于氧（例如硫）的碎片的转移，以及诸如氧气的NR和CR2等基团，具有氧气。具有重大实际意义的许多化学反应涉及氧原子的运动，该氧原子最初附着于另一个位置，该位置附着在该位置上，该位置附着于完全不同的分子上。其他化学实体（硫原子，小有机碎片）参与与这些简单的原子转移过程相似的化学变化。博士。 Espenson和Bakac将调查几种有望大大了解原子转移反应的基本原理的希望。这些系统中至少有两个也具有主要和直接的实际利益。高氯酸盐离子受到的污染是美国许多地方的新兴环境危害。原子转移减少是破坏高氯酸盐离子的最佳方法。一氧化氮（NO）是生物生物中重要的信号传导剂。该物种的功能受到原子转移过程的极大影响。这项研究中寻求的基本理解将在这些和其他重要过程中持续下去。