Dynamics of Mediated Electrochemical Synthesis in Microemulsions

该项目的目标是发展对微乳液成分、催化膜和反应物的动态相互作用如何影响电化学系统中的反应速率的基本理解。研究结果将指导专门为微乳液设计的新电极和反应系统的开发。电化学加成和环化反应将最终应用于合成精细化学品，包括内酯、信息素、光学活性烯烃和醇。需要解决的一个关键问题是胶束表面活性剂对催化剂形式势和催化活性的影响。在微乳液中，专门用于碳-碳键形成合成的新型催化电极将得到开发。探讨了聚赖氨酸-钴络合膜的改性效果。微乳液的组成和催化涂层的性质将调整为最佳的反应速率和关键反应的途径。这项工作的广泛影响将为在相对廉价、低毒的水基介质中设计高效的介导电化学合成工艺提供基本指导。

The objective of this project is the development of a fundamental understanding of how dynamic interactions involving microemulsion constituents, catalytic films, and reactants influence reaction rates in electrochemical systems. Results will guide the development of new electrodes and reaction systems designed specifically for microemulsions. Electrochemical addition and cyclization reactions will be targeted for ultimate application to the synthesis of fine chemicals including lactones, pheromones, and optically active olefins and alcohols. A key issue to be addressed is the influence of micellized surfactant within catalytic polymer layers on catalyst formal potentials and catalytic activity. New catalytic electrodes specifically for carbon-carbon bond forming syntheses in microemulsions will be developed. Effects of property-altering modifications of polylysine-cobalt complex films will be explored. Compositions of microemulsions and properties of catalytic coatings will be tuned for best reaction rates and pathways for key reactions. The broad impact of this work will be to provide fundamental guidance for the design of efficient mediated electrochemical synthetic processes in relatively inexpensive, low toxicity, water based media.