CAREER: Condensations Involving Fragmentations and the Incorporation of Inquiry Based Learning into the University Curriculum

本研究的重点是阴离子和光化学缩合反应的发展。当与阴离子断裂反应相结合时，这些转化将产生高度功能化的5-10元环体系，包括那些存在于生物活性类膜天然产物中的环体系。该项目的教育部分包括K-12科学推广和本科阶段的课程开发。在研究生阶段，未来的教育工作者将被介绍用外行术语描述化学研究的方法。通过这个奖项，有机和大分子化学项目支持亚利桑那大学化学系的Jon D. Rainier博士的研究和教育工作。雷尼尔教授将专注于开发适用于制备具有重要生物学特性的复杂分子的合成方法。雷尼尔博士的教育活动包括在本科阶段的推广工作和课程开发。

The focus of this research is the development of anionic and photochemical condensation reactions. When combined with anionic fragmentation reactions, these transformations will produce highly functionalized 5-10 membered ring systems including those present in the biologically active cembranoid natural products. The educational component of the project includes K-12 science outreach and curriculum development at the undergraduate level. At the graduate level, future educators will be introduced to ways of describing chemical research in layman's terms. With this award, the Organic and Macromolecular Chemistry Program is supporting the research and educational efforts of Dr. Jon D. Rainier of the Department of Chemistry at the University of Arizona. Professor Rainier will focus his research on the development of synthetic methodology applicable to the preparation of complex molecules with important biological properties. Dr. Rainier's educational activities include outreach efforts and curriculum development at the undergraduate level.