NANOSCALE: Nanostructured Composites via Biomimetic Processing

PI的建议是创造一种新型的纳米结构陶瓷复合材料，它可以模拟假层状（平行纤维）骨的结构。这些复合材料将有增强的韧性和高强度，由于纳米晶陶瓷颗粒排列在有序的胶原蛋白基质。这种材料将有特殊的应用，作为骨移植替代品，用于修复临界大小的骨缺损。此外，通过控制纳米结构来调节性能将为结构应用的聚合物-陶瓷复合材料的发展提供一个总体策略

9986333DouglasThe PI's propose to create novel nanostructured ceramic composites which mimic the structure of pseudolamellar (parallel-fibered) bone. These composites will have enhanced toughness and high strength due to the arrangement of nanocrystalline ceramic particles within an ordered collagen matrix. Such materials will have specific applications as bone-graft substitutes for repair of critical size osseous defects. In addition, the regulation of properties through control of nanostructure will demonstrate a general strategy for the development of polymer-ceramic composites for structural applications.***