NANOSCALE: Nanoscale Magnetics in Biology

NANOSCALE：生物学中的纳米级磁学

• 批准号: 9986525
• 负责人: Robert Austin
• 金额: $ 10万
• 依托单位: Princeton University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9986525&HistoricalAwards=false
• 关键词: NANOSCALE; Nanoscale; Magnetics; Biology

This project will explore the fabrication and use of micro to nano scale ferromagnetic structures, which will be used to isolate and fractionate biological objects. The initial emphasis will be on the interaction of the fabricated structures with ferro and superparamagnetic beads which have been coated with biologically specific antibodies. The extremely high magnetic field gradients possible with nanofabricated magnetic structures can be used to achieve extremely specific cell capture and isolation. The initial emphasis will also be on conventional nickel-based thin film magnetics, although we hope to begin fabrication of higher permeability multilayer magnetic materials and explore writing magnetic domains directly on engineered magnetic disk surfaces.

该项目将探索微纳尺度铁磁结构的制造和使用，这种结构将用于分离和分离生物物体。最初的重点将是制作的结构与涂有生物特异性抗体的铁珠和超顺磁珠的相互作用。利用纳米软磁结构可能具有的极高的磁场梯度可用于实现极特定的细胞捕获和隔离。最初的重点也将是传统的镍基薄膜磁性材料，尽管我们希望开始制造更高磁导率的多层磁性材料，并探索在工程磁盘表面直接写入磁区。