Single-Molecule Motors

本研究的重点是分子马达的合成。利用活性羧基中间体的形成和环应变的缓解，探索了能量驱动键在优选方向上旋转的概念。这个概念的第二个测试将依赖于光化学亲核芳香族取代。有机和大分子化学项目用这个奖项来支持俄勒冈大学化学系Bruce P. Branchaud博士的研究。Branchaud教授将专注于系统研究分子的设计、合成和评价，这些分子应该能够作为单分子马达。当前项目的主要目标将是测试碳碳键在优选方向上受控的能量驱动旋转的概念。在未来，这项研究可能会对单分子电机驱动装置的制备产生更广泛的影响。这个项目的领域应该激发学生的想象力，并为他们提供良好的培训。

The focus of this research is the synthesis of molecular motors. The concept of energy-driven bond rotation in a preferred direction will be explored using the formation of activated carboxyl intermediates and the relief of ring strain. A second test of the concept will rely on photochemical nucleophilc aromatic substitution. With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Bruce P. Branchaud of the Department of Chemistry at the University of Oregon. Professor Branchaud will focus his work on the systematic study of the design, synthesis and evaluation of molecules which should be capable of acting as single-molecule motors. The main objective of the current project will be to test the concept for controlled energy-driven rotation about C-C bonds in a preferred direction. In the future, the research could lead to broader impact in the preparation of working single-molecule motor-driven devices. The field of the project is one that should spark the imaginations of students and provide them with excellent training.