Metal Nanoshperes Modified With Molecular Receptors

用分子受体修饰的金属纳米球

• 批准号: 0072034
• 负责人: Angel Kaifer
• 金额: $ 32.5万
• 依托单位: University of Miami
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0072034&HistoricalAwards=false
• 关键词: Metal; Nanoshperes; Modified; Molecular; Receptors

While metal clusters, metal colloidal particles and semiconductor nanocrystals have been very attractive subjects of research work for several decades, the last few years have witnessed a clear upsurge of interest in metal and semiconductor particles with nanometer dimensions. The rapidly increasing number of research publications in this field correlates with the recent development of methodology to chemically modify the surface of these particles with organic monolayers, which can stabilize and modulate the physical and chemical properties of the nanoparticles. This research project concentrates on the preparation and characterization of metal (gold, platinum and palladium) nanoparticles modified with monolayers of molecular receptors. The key concept driving this research work is that the molecular recognition properties of the surface-immobilized hosts may be combined with the intrinsic properties of the nanoparticles to yield materials with novel and interesting properties. For instance, the catalytic ability of platinum and palladium surfaces may be modulated by the binding properties of the hosts to produce new catalysts with enhanced or modified selectivity. Surface modified nanoparticles can also be utilized for the preparation of novel composite materials and for the development of new types of sensors.%%%The proposed research work will increase our fundamental knowledge of these inorganic/organic composite materials. The initial stages of the work will focus on the characterization of gold nanospheres prepared by methods already developed in the P.I.'s laboratory. As this work moves forward, efforts will gradually turn to the preparation of platinum and palladium nanoparticles modified with molecular hosts, their characterization and their use as new catalysts.In addition to the scientific significance of the proposed work, funding of this proposal will allow the continued training and development of underrepresented scientists in the P.I.'s group. During the 1990's, five out of a total of eight Ph.D. graduates from the group were of Hispanic origin. The only two students obtaining a M.S. degree for the group were also Hispanic. Currently, four out of a total of nine graduate students in the group are also Hispanic.

虽然金属簇、金属胶体颗粒和半导体纳米晶体几十年来一直是非常有吸引力的研究课题，但最近几年人们对纳米尺寸金属和半导体颗粒的兴趣明显高涨。 该领域研究出版物数量的迅速增加与最近用有机单层化学修饰这些颗粒表面的方法的发展相关，这种方法可以稳定和调节纳米颗粒的物理和化学性质。 该研究项目集中于单层分子受体修饰的金属（金、铂和钯）纳米粒子的制备和表征。 推动这项研究工作的关键概念是表面固定主体的分子识别特性可以与纳米颗粒的固有特性相结合，产生具有新颖有趣特性的材料。 例如，铂和钯表面的催化能力可以通过主体的结合特性来调节，以产生具有增强或改进的选择性的新催化剂。 表面改性纳米颗粒还可用于制备新型复合材料和开发新型传感器。%%%所提出的研究工作将增加我们对这些无机/有机复合材料的基础知识。 该工作的初始阶段将重点关注通过 P.I. 实验室已开发的方法制备的金纳米球的表征。 随着这项工作的推进，工作将逐渐转向用分子主体修饰的铂和钯纳米粒子的制备、其表征以及它们作为新催化剂的用途。除了拟议工作的科学意义外，该提案的资助还将允许对 P.I. 小组中代表性不足的科学家进行持续培训和发展。 20 世纪 90 年代，共有 8 名博士学位，其中有 5 名获得博士学位。该团体的毕业生都是西班牙裔。 仅有的两名获得硕士学位的学生该群体的学位也是西班牙裔。 目前，该小组总共九名研究生中，有四人也是西班牙裔。