Acquisition of a Nanoparticle Analysis Ensemble

CTS-0079612西奥多W.科罗拉多州兰道夫大学MRI：纳米颗粒分析系统的获得摘要该资助支持购买一组仪器，这些仪器提供对各种类型的微粒和纳米颗粒进行分析和表征的能力。 其中一种仪器Quantachrome Autosorb 1-C是一种多用途设备，用于通过气体吸附/解吸方法测定表面积和孔径分布以及表面位置特性。 第二个是ZetaPlus，可以测量从胶体大小到30微米直径的颗粒的zeta电位。 该设备具有相位分析光散射选项，可提高电泳迁移率测量的灵敏度。 第三次收购是Aerosizer DSP干粉粒度分析仪，结合激光光学技术，可以测量0.2至700微米的粒度分布。 最后一项是TSI GEMMA法粒度分析仪。 该装置产生悬浮颗粒的气溶胶，干燥液滴，然后测量电场中剩余颗粒的流动性。 这里的尺寸测量下限对应于分子量为6000的蛋白质分子。纳米技术在许多实际领域都有发展前景。 使用这些仪器表征纳米颗粒的研究人员正在探索新陶瓷材料的高温合成，基因治疗，受控药物输送，粉末中蛋白质的稳定化，纳米颗粒材料的生产和处理以及生物技术的应用。 这些高灵敏度测量仪器的可用性提高了其观测的准确性和精确度，并增强了其结果的重要性。

CTS-0079612Theodore W. RandolphUniversity of ColoradoMRI: Acquisition of a Nanoparticle Analysis EnsembleAbstractThis grant supports the purchase of a group of instruments that provide the capability of analysis and characterization of various types of microparticles and nanoparticles. One instrument , a Quantachrome Autosorb 1-C, is a multipurpose device for determining surface areas and pore-size distributions as well as surface-site properties by gas adsorption/desorption methods. A second, a ZetaPlus, can measure zeta potential on particles from colloidal size up to 30-microns diameter. This device has a phase-analysis light-scattering option that increases the sensitivity of electrophoretic mobility measurements. A third acquisition is an Aerosizer DSP dry powder size analyzer, with supersonic gas entrainment of particles combined with laser optics, which can measure particle-size distributions from 0.2 to 700 microns. The last item in the ensemble is a TSI GEMMA-method size analyzer. This device creates an aerosol of suspended particles, dries the droplets, and then measures mobility of the remaining particles in an electric field. The lower limit on size measurement here corresponds to a protein molecule with molecular weight of 6000.Nanotechnology promises advances in many practical fields. The researchers using these instruments for characterization of nanoparticles are exploring applications in high-temperature synthesis of new ceramic materials, gene therapy, controlled drug delivery, protein stabilization in powders, production and treatment of nanoparticulate materials, and biotechnology. The availability of these highly sensitive measurement instruments increases the accuracy and precision of their observations and enhances the significance of their results.