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Neurobiology Laboratory Experience for Biology Majors and Other Advanced Students

Neurobiology Laboratory Experience for Biology Majors and Other Advanced Students
生物学专业和其他高级学生的神经生物学实验室经验
批准号:
0087886
负责人:
James Murray
金额:
$5.91万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-01-01 至 2003-12-31

项目摘要

项目成果

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中文摘要
翻译
生物科学(61)该项目通过在实验神经生物学实验室部分使用计算机化工作站,加强基础科学课程。实验神经生物学是围绕实验室组成部分,并提供了大量的调查方法。学生学习现代神经生物学技术,包括:细胞内记录,细胞外记录,动作电位辨别,神经元束追踪,神经元染色和成像。这些技术是使用模型无脊椎动物的准备工作,让新手学生成功地记录从神经系统和执行实验,在每周三个小时的时间。许多实验室会议是从国家科学基金会资助的项目Crawdad的调查改编,我们正在开发基于其他无脊椎动物的几个新活动。每个学生设计并进行一个独立的为期四周的调查,最终在口头报告和网页说明他们的调查结果。这些工作站还使其他五门生理学/细胞生物学课程的实验室活动受益。此外,这种设备大大扩大了本科生获得神经科学独立研究经验的机会。最后,该设备还使我们能够将神经科学实验室经验整合到职前教师所需的两门科学教育课程中。
英文摘要
Biological Sciences (61) This project is strengthening the basic science curriculum through use of computerized work stations in the laboratory component of Experimental Neurobiology. Experimental Neurobiology is structured around the laboratory component, and provides a heavily investigative approach. Students learn modern neurobiology techniques including: intracellular recording, extracellular recording, action potential discrimination, neuronal tract tracing, and neuron staining and imaging. These techniques are learned using model invertebrate preparations that allow novice students to successfully record from nervous systems and perform experiments in a three-hour period each week. Many laboratory sessions are adaptations of investigations from the NSF-funded Project Crawdad, and we are developing several new activities based on other invertebrates. Each student designs and carries out an independent four-week investigation culminating in an oral presentation and a web page illustrating their findings. The work stations are also benefiting the laboratory activities in five other physiology/cell biology courses. Also, this equipment is greatly expanding opportunities for undergraduates to gain an independent research experience in neuroscience. Finally, the equipment is also allowing us to integrate a neuroscience laboratory experience in two science education courses required for pre-service teachers.
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