U. S. Germany Cooperative Research: Lateral Mobility of Transmembrane Proteins in Polymer-tethered Phospholipid Bilayers Studied Via Single Molecule Fluorescence Imaging

美德合作研究：通过单分子荧光成像研究聚合物束缚的磷脂双层中跨膜蛋白的横向移动性

• 批准号: 0089604
• 负责人: Christoph Naumann
• 金额: $ 1.73万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0089604&HistoricalAwards=false
• 关键词: U.; S.; Germany; Cooperative; Research

0089604NaumannThis award supports Christoph Naumann and students from Indiana University-Purdue in a collaboration with Eva-Kathrin Schmidt of the Max Planck Institute for Biochemistry in Munich, Germany. The research focus is on development of appropriate artificial membrane architectures to allow studies of specific interactions of encoded proteins. There will be a great demand for such studies once the human genome has been mapped. This project uses the complementary facilities and expertise of the U.S. and German groups: the U.S. side provides detailed knowledge about state-of-the-art membrane architectures for transmembrane proteins and the equipment necessary to make pertinent measurements; the German counterpart has expertise related to the preparation and characterization of the transmembrane proteins to be used in the research. This joint collaborative research effort also presents junior researchers with the opportunity to work internationally, and the work done on this proposal will help institutionalize the relationship between the German and U.S. research groups.

0089604Naumann该奖项支持Christoph Naumann和印第安纳大学普渡大学的学生与德国慕尼黑马克斯普朗克生物化学研究所的Eva-Kathrin Schmidt的合作。研究重点是开发适当的人工膜结构，以研究编码蛋白质的特定相互作用。一旦人类基因组被绘制出来，这类研究将会有很大的需求。该项目利用了美国和德国团队的互补设施和专业知识：美国方面提供了关于跨膜蛋白质的最先进的膜结构的详细知识和进行相关测量所需的设备；德国同行拥有与研究中使用的跨膜蛋白的制备和表征相关的专业知识。这项联合合作研究工作也为初级研究人员提供了在国际上工作的机会，这项提案所做的工作将有助于使德国和美国研究小组之间的关系制度化。