Acquisition of a Time-Resolved Step-Scan Fourier Transform Infrared Spectrometer

在化学研究仪器和设施 (CRIF) 计划的支持下，杜克大学化学系将购买一台时间分辨步进扫描傅里叶变换红外光谱仪。 该仪器将支持多个领域的研究，包括a）黑色素光反应中间体的表征； b) MLCT态的电子分布和血红素蛋白的光动力学； c) 用于探测 DNA 电子转移的新型钌 (II) 配合物的激发态电子结构； d) 研究铁(III)-铁载体螯合反应中的第二配位壳层动力学； e) 评估 s-亚硝化血红蛋白中一氧化氮的形式氧化还原态； f) 蛋白质折叠动力学。 傅里叶变换光谱技术在学术和工业研究中的普遍有效性已得到牢固确立。 现在许多高级光谱课程通常都包含傅里叶变换光谱学的教学。 时间分辨能力是傅里叶变换光谱学最重要的最新发展之一，正在迅速被各种研究探索。 最近的应用包括生物、聚合物和环境研究。 这些研究将在许多领域产生影响，特别是生物化学。

With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Duke University will acquire a time-resolved, step-scan Fourier-transform infrared spectrometer. This instrument will support research in a number of areas, including a) characterization of the intermediates in the photoreactions of melanins; b) electron distribution in MLCT states and photo dynamics of heme proteins; c) excited state electronic structure of novel ruthenium (II) complexes used for probing DNA electron transfer; d) investigation of second-coordination shell dynamics in iron (III)-siderophore chelation reactions; e) evaluation of the formal redox state of nitric oxide in s-nitrosated hemoglobins; and f) protein folding dynamics. The general effectiveness of Fourier transform spectroscopic techniques in academic and industrial research has been firmly established. Many advanced spectroscopic courses now routinely include the teaching of FT spectroscopy. The time-resolved capability is one of the most important recent developments in FT spectroscopy that is rapidly being explored for all kinds of research. Recent applications include biological, polymer, and environmental studies. These studies will have an impact in a number of areas, especially biochemistry.