MRI: Acquisition of a femtosecond laser system for time-resolved studies using Arizona State University's (ASU) Compact X-ray Light Source (CXLS)
MRI:使用亚利桑那州立大学 (ASU) 的紧凑型 X 射线光源 (CXLS) 获取飞秒激光系统,用于时间分辨研究
基本信息
- 批准号:2019014
- 负责人:
- 金额:$ 70.74万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-10-01 至 2024-09-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
An award is made to Arizona State University (ASU) to acquire a state-of-the-art Coherent Astrella, high power, ultrafast laser system (Astrella) that will be used to trigger dynamic processes in natural, engineered and quantum materials as imaged using ASU’s first-of-its-kind compact X-ray light source (CXLS). A postdoctoral associate will help integrate the Astrella laser with the CXLS providing a rich training opportunity using world-class tools (CXLS is a national laboratory-level tool at a university), interdisciplinary topics, and building diverse collaborations that may lead to high ranking publications and career networking. Undergraduate and graduate students from biology, chemistry, physics, data science, and engineering will play key roles during commissioning and laser-driven X-ray science experiments by assisting with accelerator and beamline engineering and maintenance, beamline configuration, sample preparation and delivery, data collection, data analysis and structural modeling.The capabilities of the Astrella-CXLS system will attract a large user community—primarily from the Southwestern US, but also leading experts across the world—including 33 users committed from eight domestic universities, two international universities (Spain, Germany) and one national lab. This will enable researchers to conduct cutting-edge experiments to 1) unravel the secrets of photosynthesis with important impacts in agriculture, forests, and oceans, as well as light-sensing in bacteria and human vision; 2) develop completely new science for human engineered proteins and synthetic catalysts, which have not been previously studied at national X-ray laser facilities, and will enable next generation technologies for converting solar energy to fuels; 3) initiate light-driven changes in novel quantum materials with the ultimate goal of manipulating superconductors and spin-based quantum computers. The potentially transformative results from the research enabled by the Astrella-CXLS system will be disseminated in peer-reviewed publications and at scientific meetings across a broad range of scientific fields, including biology, chemistry, quantum physics, materials science, and the earth and planetary sciences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
亚利桑那州立大学(ASU)获得了一项奖项,以获得最先进的相干Astrella、高功率、超快激光系统(Astrella),该系统将用于触发自然、工程和量子材料的动态过程,并使用ASU首创的紧凑x射线光源(CXLS)进行成像。博士后助理将帮助整合Astrella激光器和CXLS,提供丰富的培训机会,使用世界一流的工具(CXLS是一所大学的国家实验室级工具),跨学科主题,并建立多样化的合作,可能导致高排名的出版物和职业网络。来自生物学、化学、物理学、数据科学和工程学的本科生和研究生将在调试和激光驱动的x射线科学实验中发挥关键作用,协助加速器和光束线工程和维护、光束线配置、样品制备和交付、数据收集、数据分析和结构建模。Astrella-CXLS系统的能力将吸引一个庞大的用户群体——主要来自美国西南部,但也包括来自世界各地的领先专家——包括来自8所国内大学、2所国际大学(西班牙、德国)和一个国家实验室的33名用户。这将使研究人员能够进行尖端的实验,以1)解开光合作用的秘密,光合作用对农业、森林和海洋以及细菌和人类视觉的光敏有重要影响;2)开发人类工程蛋白和合成催化剂的全新科学,这是以前没有在国家x射线激光设施中研究过的,并将使下一代太阳能转化为燃料的技术成为可能;3)启动新型量子材料的光驱动变化,最终目标是操纵超导体和基于自旋的量子计算机。Astrella-CXLS系统带来的潜在变革性研究成果将在同行评议的出版物和广泛科学领域的科学会议上传播,包括生物学、化学、量子物理学、材料科学以及地球和行星科学。该奖项反映了美国国家科学基金会的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Petra Fromme其他文献
NMR Studies on Membrane Protein OEP16
- DOI:
10.1016/j.bpj.2011.11.1448 - 发表时间:
2012-01-31 - 期刊:
- 影响因子:
- 作者:
James D. Zook;Michael F. Brown;Neil Jacobsen;Guangxin Lin;Petra Fromme - 通讯作者:
Petra Fromme
Sources of inspiration
灵感的来源
- DOI:
10.1038/505620a - 发表时间:
2014-01-29 - 期刊:
- 影响因子:48.500
- 作者:
Sean McSweeney;Petra Fromme - 通讯作者:
Petra Fromme
Cryofold: Determining Protein Structures and Data- Guided Ensembles from Cryo-Em Density Maps
Cryofold:从 Cryo-Em 密度图确定蛋白质结构和数据引导的整体
- DOI:
10.2139/ssrn.3866834 - 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
M. Shekhar;Genki Terashi;C. Gupta;Daipayan Sarkar;Gaspard Debussche;N.N.S. Sisco;Jonathan Nguyen;Arup Mondal;James D. Zook;J. Vant;Petra Fromme;Wade Van Horn;Emad Tajkhorshid;Diasuke Kihara;Ken Dill;Alberto Perez;A. Singharoy - 通讯作者:
A. Singharoy
Design and Assembly of an Artificial Oxygen-Evolving Complex in DNA Nanostructures
- DOI:
10.1016/j.bpj.2011.11.3475 - 发表时间:
2012-01-31 - 期刊:
- 影响因子:
- 作者:
Kimberly N. Rendek;Chad Simmons;Jesse Bergkamp;Justin Flory;Chenxiang Lin;Ingo Grotjohann;Raimund Fromme;Devens Gust;Hao Yan;Yan Liu;Petra Fromme - 通讯作者:
Petra Fromme
Femtosecond dynamics of rhodopsin revealed by X-ray laser
- DOI:
10.1016/j.bpj.2022.11.1208 - 发表时间:
2023-02-10 - 期刊:
- 影响因子:
- 作者:
Michael F. Brown;Thomas D. Grant;Suchithranga M.D.C. Perera;Leslie Salas-Estrada;Andrey V. Struts;Konstantinos Karpos;Udeep Chawla;Steven D.E. Fried;C. Swathi K. Menon;Nipuna Weerasinghe;Domingo Meza;Derek Mendez;Alan Grossfield;Petra Fromme;Richard A. Kirian - 通讯作者:
Richard A. Kirian
Petra Fromme的其他文献
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{{ truncateString('Petra Fromme', 18)}}的其他基金
RAPID: IIBR: Instrumentation: Time-resolved studies of the SARS-CoV-2 endonuclease NP15
RAPID:IIBR:仪器:SARS-CoV-2 核酸内切酶 NP15 的时间分辨研究
- 批准号:
2031343 - 财政年份:2020
- 资助金额:
$ 70.74万 - 项目类别:
Standard Grant
Structure and Function of Supercomplexes of Photosystem I with its Peripheral Antenna Systems in Green Algae and Cyanobacteria
绿藻和蓝藻中光系统 I 及其外围天线系统超级复合体的结构和功能
- 批准号:
0417142 - 财政年份:2004
- 资助金额:
$ 70.74万 - 项目类别:
Continuing Grant
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