MRI: Acquisition of a Time-Resolved Fluorescence Instrument for Chemistry Research and Education

凭借主要研究仪器（MRI）项目的这项奖励，Patrick M. Hare教授和他的同事Stefan Paula和Keith a . Walters将把一个荧光计升级为皮秒时间分辨率的可变激发波长仪器，这将加强北肯塔基大学的研究和教育项目。三个研究领域将受益于新的能力：1)富勒烯-过渡金属体系的有机金属超分子化学；2) Sarco/内质网atp酶（SERCA）新型抑制剂的光谱表征；3)内分泌干扰物的光物理。发射寿命荧光分光光度计测量从被光源提升到激发态的样品发出的光的时间衰减。这提供了对化学和生物系统中能量转移和损失机制的见解。它可以揭示底物如何与酶相互作用的信息，或者可以用于太阳能电池的新材料，以及其他可能的应用。该仪器将用于本科生的研究和实验课。

With this award from the Major Research Instrumentation (MRI) program, Professor Patrick M. Hare and his colleagues Stefan Paula and Keith A. Walters will upgrade a fluorometer to a picosecond time-resolved, variable excitation wavelength instrument that will enhance both the research and education programs at Northern Kentucky University. Three areas of research will be benefit from the new capability: 1) Organometallic Supramolecular Chemistry of Fullerene-Transition Metal Systems; 2) Spectroscopic Characterization of Novel Inhibitors of the Sarco/endoplasmic Reticulum ATPase (SERCA); and 3) Photophysics of Endocrine Disrupting Compounds. Emission lifetime fluorescence spectrophotometers measure the time decay of the light emitted from a sample that has been promoted to an excited state by a light source. This provides insight on the mechanisms of energy transfer and loss in chemical and biological systems. It can reveal information on how substrates interact with enzymes or new materials can be used in solar cells, among other possible applications. The instrument will be used in research and laboratory classes by undergraduate students.