CAREER: Photolysis of Alkylazides in Solution and in Crystals

有了这个职业奖，有机和高分子化学计划支持博士安娜D。Gudmundsdottir在俄亥俄州辛辛那提的辛辛那提大学化学系。 该研究涉及形成，检测和调查的反应性的烷基氮烯中间体在溶液中，并在固态，强调三重氮烯在烷基叠氮化物的光解形成。 要研究的叠氮化物，使用维斯/紫外和红外光谱和产品分析的组合，包括叠氮苯乙酮，β-，γ-和δ-叠氮芳基酮，苄基叠氮，和氟化2-叠氮乙基benzen.Dr. Gudmundsdottir建议研究一类高活性有机分子的光谱特性和反应性，这些分子含有一个饱和碳原子与一个不饱和氮原子结合。 这些氮烯将使用激光闪光光解在溶液或结晶固体中产生，并且可能含有两个具有平行或反平行自旋的电子（三重态或单重态电子状态），通常导致不同的产物。 更好地理解这些反应在固态下，预计将导致更好地设计新材料的有机晶体。 可能的应用包括光刻、生物分子的光亲和标记和有机磁体。 学生们将通过开展研究和参加研讨会课程来学习，在研讨会课程中，他们将接触到一些成功的科学家，包括来自行业和代表性不足的少数民族的代表。 研讨会将帮助学生决定什么样的职业道路，遵循一旦他们离开辛辛那提大学。

With this CAREER award the Organic and Macromolecular Chemistry Program supports the work of Dr. Anna D. Gudmundsdottir in the Department of Chemistry at the University of Cincinnati in Cincinnati, Ohio. The research involves forming, detecting, and investigating the reactivity of alkyl nitrene intermediates in solution and in the solid state, emphasizing triplet nitrenes formed in the photolysis of alkyl azides. The azides to be studied, using a combination of vis/uv and IR spectroscopies and product analysis, include azidoacetophenone, beta-, gamma-, and delta-azidoarylketones, benzyl azide, and fluorinated 2-azidoethyl benzene.Dr. Gudmundsdottir proposes to study the spectroscopic properties and reactivity of a class of highly reactive organic molecules which contain a saturated carbon atom bound to an unsaturated nitrogen atom. These nitrenes will be generated in solution or in crystalline solids using laser flash photolysis, and may contain two electrons with parallel or antiparallel spins (triplet or singlet electronic states), often leading to different products. Better understanding of these reactions in the solid state is expected to lead to better design of organic crystals for new materials. Possible applications include photolithography, photoaffinity labels for biological molecules, and organic magnets. Students will learn both from carrying out the research and by participating in a seminar course where they will be exposed to a number of successful scientists, including representatives from industry and from underrepresented minorities. The seminars will help the students decide what career paths to follow once they leave the University of Cincinnati.