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RUI: Investigation of the Kinetics and Mechanism for Covalent Binding of Proteins to Thin-Films

RUI: Investigation of the Kinetics and Mechanism for Covalent Binding of Proteins to Thin-Films
RUI:蛋白质与薄膜共价结合的动力学和机制研究
批准号:
0094392
负责人:
Alice Deckert
金额:
$9.64万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-05-01 至 2003-04-30

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中文摘要
翻译
该RUI奖授予阿勒格尼学院的Alice Deckert教授,题为“蛋白质与薄膜共价结合的动力学和机制的研究”,由分析和表面化学项目支持。研究的目的是全面研究蛋白质与薄膜结合的动力学和机制。表面等离子体共振(SPR)和微重力(石英晶体微天平)分析将用于帮助理解这些反应。该研究将集中于改善生物传感器的发展。Langmuir-Blodgett蛋白薄膜和自组装单层都将被检测。这项研究是跨学科的,将影响表面分析、分析化学和生物化学等领域。这项由本科生进行的研究将具有重要的科学意义和丰富的教育意义。研究结果将对社会产生影响,促进生物传感器技术的发展。
英文摘要
This RUI award to Professor Alice Deckert of Allegheny College entitled "Investigation of the Kinetics and Mechanism for Covalent Binding of Proteins to Thin Films" is supported by the Analytical and Surface Chemistry Program. The goal of the research is the comprehensive study of the kinetics and mechanism of protein binding to thin films. Surface plasmon resonance (SPR) and microgravimetric (Quartz Crystal Microbalance) analyses will be used to help understand these reactions. The research will focus on improving the development of biosensors. Both Langmuir-Blodgett protein thin films and self-assembled monolayers will be examined. The research is interdisciplinary and will impact the fields of surface analysis, analytical chemistry and biochemistry.This research, to be performed by undergraduates, will be scientifically significant and educationally rich. The results will impact society in furthering the development of biosensor technology.
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Investigation of the Kinetics and Mechanism for Reactions at Thin-Film Surfaces
  • 批准号:
    0307043
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $12.75万
  • 财政年份:
    2003
  • 负责人:
    Alice Deckert
  • 依托单位:
海外基金