MRI: Acquisition of a CCD Single Crystal X-ray Diffraction System for a Partnership of Maine Institutions

MRI：为缅因州机构合作伙伴采购 CCD 单晶 X 射线衍射系统

• 批准号: 0115832
• 负责人: Rebecca Conry
• 金额: $ 25.72万
• 依托单位: Colby College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2004-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0115832&HistoricalAwards=false
• 关键词: MRI; Acquisition; CCD; Single; Crystal

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Colby College will acquire a X-ray diffractometer with CCD detector for small molecule diffractometry. This equipment will be used by five educational institutions in Maine: Colby College, Bates College, Bowdoin College, the University of Southern Maine and the University of Maine. The X-ray CCD diffractometer will enhance research in a number of areas including 1) studies of copper-arene chemistry; 2) development of new synthetic methods of selected natural products; 3) synthesis of polycyclic cage compounds with unusual architecture; 4) structure-function relationships in metalloenzymes and metalloenzymes mimics; and 5) production of C-2 symmetric lanthanocene catalyst systems and their utility in the construction of chiral molecules. The X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of the molecule relative to the neighboring molecules. These studies will have an impact in a number of areas, including organic and natural products synthesis plus biological, organometallic and materials areas of inorganic chemistry. The instrument will play a major supporting role in the research efforts of all of the participating institutions, which range from bachelor's level to Ph.D.-granting schools. In addition, the diffraction system will be used for the formal education of students in advanced chemistry courses utilizing the capability of the diffractometer to be run off site.

在主要研究仪器（MRI）计划的支持下，科尔比学院化学系将获得一台带有CCD检测器的X射线衍射仪，用于小分子衍射。该设备将由缅因州的五所教育机构使用：科尔比学院、贝茨学院、鲍登学院、南缅因州大学和缅因州大学。 X射线CCD衍射仪将促进多个领域的研究，包括：1）铜-芳烃化学研究; 2）选定天然产物的新合成方法的开发; 3）具有不寻常结构的多环笼化合物的合成; 4）金属酶和金属酶模拟物的结构-功能关系;和5）C-2对称镧茂催化剂体系的制备及其在手性分子构建中的应用。 X射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于相邻分子的空间排列的准确信息。 这些研究将在许多领域产生影响，包括有机和天然产物合成以及无机化学的生物，有机金属和材料领域。 该仪器将在所有参与机构的研究工作中发挥重要的支持作用，这些机构的范围从学士学位到博士学位。授予学校。 此外，衍射系统将用于高级化学课程的学生的正规教育，利用衍射仪的能力可以在现场外运行。