MRI: Acquisition of a CCD X-ray Diffractometer for Chemical Research and Education

在主要研究仪器（MRI）项目的支持下，瓦萨学院化学系将获得一台带有CCD探测器的单晶x射线衍射仪。该仪器将促进若干领域的研究：(1)顺磁性和空气敏感配位化合物的研究；(2)微晶扩展结构网络材料的结构研究；(3)巨富勒烯的孪生衍生物的研究；(4)有机阴离子受体和合成肽模拟物的氢键结构研究；(5)生物活性小分子和天然产物化合物的分析。x射线衍射仪可以精确测量分子的完整三维结构，包括键的距离和角度，并提供分子相对于邻近分子的空间排列的准确信息。这些研究将在许多领域产生影响，特别是材料化学、生物化学和药物化学。

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Vassar College will acquire a single-crystal X-ray diffractometer with CCD detector. This instrument will facilitate research in a number of areas: (1) the investigation of paramagnetic and air-sensitive coordination compounds; (2) the structural investigation of microcrystalline extended structure network materials; (3) examination of twinned derivatives of giant fullerenes; (4) the study of hydrogen bonding structures exhibited by organic anion receptors and synthetic peptide mimics; and (5) the analysis of biologically active small molecule and natural product compounds. The X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of the molecule relative to the neighboring molecules. These studies will have an impact in a number of areas, especially materials chemistry, biochemistry and medicinal chemistry.