Integrating High-Field NMR Spectroscopy throughout the Undergraduate Chemistry Curriculum
Integrating High-Field NMR Spectroscopy throughout the Undergraduate Chemistry Curriculum
批准号:
0126758
负责人:
Judith Cain
金额:
$12.18万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-04-15 至 2004-03-31
中文摘要
化学(12)本项目的目的是在整个本科化学课程中引入现代多核傅里叶变换核磁共振(NMR)光谱实验。实验来自教学和研究文献,并适应特定的课程。它们旨在为学生提供广泛的NMR实践经验,以说明NMR技术的力量和多样性。实验室实验开始时,在大一时介绍1H NMR光谱学。大二使用1H和13C NMR的更严格的治疗,并在大三,学生收到介绍NMR的功率作为一种方法来研究动力学,核自旋弛豫机制,和多脉冲实验,他们探索仪器因素。在他们的高年级,学生使用各种复杂的一维和二维NMR技术(COSY,HETCOR,DEPT,INADEQUATE)来确定光谱复杂分子的结构和性质。该项目旨在积极影响所有化学和生物学专业的科学教育。此外,NMR被参与本科研究的学生广泛使用。来自附近南弗吉尼亚大学的学生也在他们的几门课程中使用该仪器,并通过参与本科生研究。
英文摘要
Chemistry (12)The purpose of this project is to introduce modern multinuclear Fourier Transform Nuclear Magnetic Resonance (NMR) Spectroscopy experiments throughout the undergraduate chemistry curriculum. Experiments are drawn from pedagogical and research literature and are adapted to specific courses. They are designed to present students with a breadth of hands-on NMR experiences to illustrate the power and variety of NMR techniques. Laboratory experiments begin with an introduction to 1H NMR spectroscopy in the freshman year. The sophomore year uses a more rigorous treatment of 1H and 13C NMR and, in the junior year, students receive an introduction to the power of NMR as a method to study kinetics, nuclear spin relaxation mechanisms, and multiple pulse experiments, and they explore instrumental factors. In their senior year, students use a variety of sophisticated one and two-dimensional NMR techniques (COSY, HETCOR, DEPT, INADEQUATE) to determine the structure and properties of spectrally complex molecules. This project is designed to positively impact the science education of all chemistry and biology majors. In addition, the NMR is being used extensively by students involved in undergraduate research. Students from nearby Southern Virginia University also are making use of the instrument in several of their courses and through their participation in undergraduate research.
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