Integrating High-Field NMR Spectroscopy throughout the Undergraduate Chemistry Curriculum

将高场核磁共振波谱学融入整个本科化学课程

• 批准号: 0126758
• 负责人: Judith Cain
• 金额: $ 12.18万
• 依托单位: Virginia Military Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-15 至 2004-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0126758&HistoricalAwards=false
• 关键词: Integrating; Field; NMR; Spectroscopy; throughout

Chemistry (12)The purpose of this project is to introduce modern multinuclear Fourier Transform Nuclear Magnetic Resonance (NMR) Spectroscopy experiments throughout the undergraduate chemistry curriculum. Experiments are drawn from pedagogical and research literature and are adapted to specific courses. They are designed to present students with a breadth of hands-on NMR experiences to illustrate the power and variety of NMR techniques. Laboratory experiments begin with an introduction to 1H NMR spectroscopy in the freshman year. The sophomore year uses a more rigorous treatment of 1H and 13C NMR and, in the junior year, students receive an introduction to the power of NMR as a method to study kinetics, nuclear spin relaxation mechanisms, and multiple pulse experiments, and they explore instrumental factors. In their senior year, students use a variety of sophisticated one and two-dimensional NMR techniques (COSY, HETCOR, DEPT, INADEQUATE) to determine the structure and properties of spectrally complex molecules. This project is designed to positively impact the science education of all chemistry and biology majors. In addition, the NMR is being used extensively by students involved in undergraduate research. Students from nearby Southern Virginia University also are making use of the instrument in several of their courses and through their participation in undergraduate research.

化学(12)这个项目的目的是在整个本科化学课程中介绍现代多核傅立叶变换核磁共振(核磁共振)谱实验。实验取材于教学和研究文献，适用于特定的课程。它们旨在为学生提供广泛的实践核磁共振体验，以说明核磁共振技术的力量和多样性。实验室实验从一年级的~1H核磁共振波谱开始。二年级使用更严格的1H和13C核磁共振处理，在三年级，学生将学习作为研究动力学、核自旋弛豫机制和多脉冲实验的方法的核磁共振的力量，并探索仪器因素。在他们的高年级，学生使用各种复杂的一维和二维核磁共振技术(COSY，HETCOR，DEPT，不充分)来确定光谱复杂分子的结构和性质。该项目旨在积极影响所有化学和生物专业的科学教育。此外，核磁共振正在被参与本科生研究的学生广泛使用。来自附近南弗吉尼亚大学的学生也在他们的几门课程中使用这种仪器，并通过参与本科生的研究。