Porphyrins, Carbaporphyrins and Related Conjugated Macrocycles

卟啉、碳卟啉和相关共轭大环化合物

• 批准号: 0134472
• 负责人: Timothy Lash
• 金额: $ 27.3万
• 依托单位: Board of Trustees of Illinois State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0134472&HistoricalAwards=false
• 关键词: Porphyrins; Carbaporphyrins; Related; Conjugated; Macrocycles

The focus of this research is to develop methodology for the preparation of porphyrins with fused pyrene rings and to test the potential for using pyrene as a platform for connecting fused porphyrin rings. In parallel studies, the synthesis, characterization and chemistry of carbaporphyrins will be investigated. Other macrocyclic systems, including tropiporphyrin, will be synthesized using "3+1" methodology and "4+1" methodology will be used to prepare carba-analogues of expanded porphyrins. Undergraduate students will be involved at all stages of the research.With this renewal Research in Undergraduate Institutions (RUI) award, the Organic and Macromolecular Chemistry Program is supporting the research efforts of Dr. Timothy D. Lash of the Department of Chemistry at Illinois State University. Dr. Lash will focus his work on the preparation of porphyrin-like chromophores and related dimeric or oligomeric systems. Porphyrins are a class of brightly colored heterocycles that serve a variety of functions in nature and the synthesis of analogues opens new avenues for the preparation of compounds with potentially interesting properties. The work will be carried out with the collaboration of undergraduate and masters level graduate students.

这项研究的重点是发展制备具有稠合芘环的卟啉的方法学，并测试利用芘作为连接稠合卟啉环的平台的可能性。在平行研究中，将研究碳卟啉的合成、表征和化学。其他大环体系，包括三苯基卟啉，将用“3+1”方法合成，“4+1”方法将用来制备扩展的卟啉的碳氢化合物类似物。本科生将参与研究的所有阶段。有了本科生机构更新研究奖(RUI)，有机和高分子化学项目将支持伊利诺伊州立大学化学系的蒂莫西·D·拉什博士的研究努力。拉什博士将把工作重点放在类似卟啉的发色团和相关的二聚体或低聚物体系的制备上。卟啉是一类颜色鲜艳的杂环化合物，在自然界中具有多种功能，类似物的合成为制备具有潜在有趣性质的化合物开辟了新的途径。这项工作将在本科生和硕士研究生的合作下进行。