Synthesis of Novel Porphyrinoids by the "3 + 1" Approach

“3 1”法合成新型卟啉类化合物

• 批准号: 9732054
• 负责人: Timothy Lash
• 金额: $ 21万
• 依托单位: Board of Trustees of Illinois State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-01 至 2002-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9732054&HistoricalAwards=false
• 关键词: Synthesis; Novel; Porphyrinoids; Approach

The focus of this research, carried out in an undergraduate setting, is the development of synthetic methodology for the preparation of porphyrins and porphyrinoids. The `3 + 1` method, wherein a monocyclic dialdehyde is condensed with a tripyrrolic structure, will be used to gain a wide range of structural variation. The scope of the protocol will be explored with the goal of producing a number of new and novel compounds. With this renewal Research in Undergraduate Institutions award, the Organic and Macromolecular Chemistry Program is supporting the research efforts of Dr. Timothy D. Lash of the Department of Chemistry at Illinois State University. In collaboration with his undergraduate participants, Dr. Lash will focus his work on the preparation of substituted porphyrin and porphyrinoid structures. The chemistry and spectroscopic properties of the the latter will be insightful and there the possibility exists that practical applications could ensue

这项在本科生环境中进行的研究的重点是开发制备卟啉和类卟啉的合成方法。 “3+1”方法，其中单环二醛与三吡咯结构缩合，将用于获得广泛的结构变化。 该协议的范围将被探索，目标是生产一些新的和新颖的化合物。 通过这一更新的本科院校研究奖，有机和高分子化学项目正在支持伊利诺伊州立大学化学系 Timothy D. Lash 博士的研究工作。 Lash 博士将与本科生合作，将工作重点放在取代卟啉和类卟啉结构的制备上。 后者的化学和光谱特性将具有深刻的洞察力，并且有可能实现实际应用