RUI: Image Aquisition and Analysis Facility for Faculty-Student Research

RUI：用于师生研究的图像采集和分析设施

• 批准号: 0200148
• 负责人: David Ribble
• 金额: $ 10.21万
• 依托单位: Trinity University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0200148&HistoricalAwards=false
• 关键词: RUI; Image; Aquisition; Analysis; Facility

Abstract A grant has been awarded to Dr. David Ribble of the Biology Department at Trinity University to fund state of the art image acquisition and analysis instrumentation and software. This equipment will be housed in the Center for Image Acquisition and Analysis, a multi-user research facility that will enhance the research capabilities of all faculty and undergraduate students in the Department of Biology at Trinity University. Trinity University will remodel an existing laboratory to provide a site for this Center and will share in the cost of the equipment and software. To satisfy the needs of this diverse research community, the Center will contain equipment and software to acquire, store, and analyze images appropriate to research studies in molecular biology, cellular biology, physiology, ecology, and evolution. To meet these needs, the following items of equipment will be purchased: a gel documentation system; a fluorescence microscope with deconvolution capabilities, digital cameras, computers, and support software. The Center for Image Acquisition and Analysis will significantly increase faculty and student research capabilities, enhancing the activities of the varied research groups within the Department of Biology. Each of these groups will make intensive use of this new facility. These ongoing research projects include the study of the following topics: The mechanisms for selective destabilization of secretory protein mRNAs at the ER Changes in ovarian gene expression during ovulation Regulation of photosystem production by a putative GTP-binding protein in Rhodospirillum centenum Paracellular permeability of tight junctions in intestinal epithelial cells Rat epidermal cell responses to radiofrequency radiation Evolution of monogamy and conservation of mammals Sociality and social parasitism in galling aphids Not only will this equipment support the ongoing research activities of faculty and students; the sensitivity, resolution, and analysis capabilities of the proposed equipment will provide opportunities for research initiatives and directions not currently possible at Trinity. Furthermore, use of this shared facility will help develop collaborative research projects between the diverse sub-disciplines within the Department of Biology.

摘要Trinity大学生物系的大卫里布尔博士获得了一笔赠款，用于资助最先进的图像采集和分析仪器和软件。该设备将被安置在图像采集和分析中心，这是一个多用户研究设施，将提高Trinity大学生物系所有教师和本科生的研究能力。 Trinity大学将改造现有的实验室，为该中心提供场地，并将分担设备和软件的费用。为了满足这个多样化的研究社区的需求，该中心将包含设备和软件，以获取，存储和分析适合于分子生物学，细胞生物学，生理学，生态学和进化研究的图像。为了满足这些需要，将购买以下设备：凝胶文件系统;具有去卷积功能的荧光显微镜、数码相机、计算机和支持软件。图像采集和分析中心将显著提高教师和学生的研究能力，加强生物系内各种研究小组的活动。每个小组都将大量使用这一新设施。这些正在进行的研究项目包括以下主题的研究：ER分泌蛋白mRNA选择性去稳定的机制排卵期间卵巢基因表达的变化Rhodocellum中一种推定的GTP结合蛋白对光系统产生的调节 Centenum肠上皮细胞紧密连接的细胞旁渗透性大鼠表皮细胞对射频辐射的反应一夫一妻制的进化和哺乳动物的保护蚜虫的社会性和社会寄生性该设备不仅将支持教师和学生正在进行的研究活动;建议的设备的灵敏度、分辨率和分析能力将为Trinity目前不可能的研究倡议和方向提供机会。此外，使用这个共享设施将有助于开发生物学系内不同子学科之间的合作研究项目。