A Novel Mechanism To Make Microfluidic Components and Systems Requiring No Mechanically Moving Parts

项目名称：宗璐Susan Hua， suny - buffalo提案编号：0201293提案题目：一种制造不需要机械运动部件的微流控元件和系统的新机制项目摘要：该研究的重点是开发一种新的驱动机制，使制造各种不需要机械运动部件的微流控元件成为可能。这种新型驱动机构是基于电化学产生气泡作为微流控系统的控制元件。这种方法本质上是低功耗的，需要一个简单的片上电子电路，并且控制元件是自修复的。在制造阀门、泵、开关和流体逻辑系统方面进行了详细的研究。实验研究还补充了气泡形成的基础研究，包括气泡成核和破裂作为压力、施加电压、流速和气泡与微通道壁之间界面条件的函数。这些研究在微生物学、生物技术、药物输送、组合化学和分析化学等领域具有基础和技术意义。教育、培训和推广活动包括研究生和本科生的实践经验，以及针对女性和少数民族的特定高中暑期项目。它为学生提供了微加工技术、薄膜生长、计量、器件制造、测试和表征等领域的重要培训。

PI's Name, Institution: Zonglu Susan Hua, SUNY-BuffaloProposal Number: 0201293Proposal Title: A Novel Mechanism to Make Microfluidic Components and Systems Requiring No Mechanical Moving PartsProject Abstract: The research is focused on developing a novel mechanism for actuation that would enable fabrication of various microfluidic components that require no moving mechanical parts. The novel actuation mechanism is based on electrochemistry to generate bubbles, which acts as control elements of a microfluidic system. This method is intrinsically low power in nature, requires a simple on-chip electronics circuitry, and the control elements are self-repairing. Detailed studies are being performed on making valves, pumps, switches, and fluid logic system. The experimental studies are being complemented with fundamental investigation of bubble formation, including bubble nucleation and collapse as a function of pressure, applied voltage, flow rate, and interface conditions between the bubble and microchannel walls. These studies are of fundamental as well as technological interest in fields ranging from microbiology, biotechnology, and drug delivery, to combinatorial and analytical chemistry. The educational, training, and outreach includes hands-on experience by graduate as well as undergraduate students, along with specific high school summer program targeted at women and minorities. It is providing students with important training in areas such as microfabrication technology, thin film growth, metrology, device fabrication, testing, and characterization.