A Novel Mechanism To Make Microfluidic Components and Systems Requiring No Mechanically Moving Parts

派的名字，机构：Zonlu Susan hua，SUNY-Buffalo Proposal编号：0201293建议标题：一种新的机制来制造不需要机械移动部件的微流控部件和系统项目摘要：研究重点是开发一种新的驱动机制，使不需要移动机械部件的各种微流控部件的制造成为可能。这种新颖的驱动机制是基于电化学产生气泡，作为微流控系统的控制元件。这种方法本质上是低功耗的，只需要简单的片上电子电路，并且控制元件是自修复的。关于制造阀门、泵、开关和流体逻辑系统的详细研究正在进行中。实验研究与气泡形成的基础研究相辅相成，包括气泡的成核和崩塌与压力、外加电压、流速和气泡与微通道壁之间的界面条件的函数关系。这些研究在从微生物学、生物技术和药物输送到组合和分析化学的各个领域都具有基础性和技术性的兴趣。教育、培训和外展包括研究生和本科生的实践经验，以及针对女性和少数族裔的特定高中暑期计划。它为学生提供微细加工技术、薄膜生长、计量、器件制造、测试和表征等领域的重要培训。

PI's Name, Institution: Zonglu Susan Hua, SUNY-BuffaloProposal Number: 0201293Proposal Title: A Novel Mechanism to Make Microfluidic Components and Systems Requiring No Mechanical Moving PartsProject Abstract: The research is focused on developing a novel mechanism for actuation that would enable fabrication of various microfluidic components that require no moving mechanical parts. The novel actuation mechanism is based on electrochemistry to generate bubbles, which acts as control elements of a microfluidic system. This method is intrinsically low power in nature, requires a simple on-chip electronics circuitry, and the control elements are self-repairing. Detailed studies are being performed on making valves, pumps, switches, and fluid logic system. The experimental studies are being complemented with fundamental investigation of bubble formation, including bubble nucleation and collapse as a function of pressure, applied voltage, flow rate, and interface conditions between the bubble and microchannel walls. These studies are of fundamental as well as technological interest in fields ranging from microbiology, biotechnology, and drug delivery, to combinatorial and analytical chemistry. The educational, training, and outreach includes hands-on experience by graduate as well as undergraduate students, along with specific high school summer program targeted at women and minorities. It is providing students with important training in areas such as microfabrication technology, thin film growth, metrology, device fabrication, testing, and characterization.