NIRT: Ink Jetting of Nanostructured Matrices for Controlled Gene Delivery

NIRT：用于受控基因传递的纳米结构基质喷墨

• 批准号: 0210238
• 负责人: Prashant Kumta
• 金额: $ 100万
• 依托单位: Carnegie-Mellon University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-15 至 2007-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0210238&HistoricalAwards=false
• 关键词: NIRT; Ink; Jetting; Nanostructured; Matrices

ABSTRACTCTS-0210238P. Kumta, L. Walker, L. Weiss, P. Campbell and J. HollingerCarnegie Mellon UniversityA novel techniques based on modification of ink jet printing technology for controlled Gene delivery and development of a new technology for tissue engineering is proposed. The PIs seek to create a biomimetic extracellular matrix with controlled temporal-spatial patterns of NanoCaPs that contains DNAs or plasmid growth factor. The controlled patterns will be created with the ink-jet technology and the performance will be evaluated in-vitro.

摘要CTS-0210238 P。库姆塔湖步行者湖韦斯，P.坎贝尔和J. Hollinger卡内基梅隆大学提出了一种基于喷墨打印技术的改进的用于受控基因递送的新技术，并开发了一种用于组织工程的新技术。 PI试图创建一种仿生细胞外基质，其具有含有DNA或质粒生长因子的NanoCaP的受控时空模式。 将使用喷墨技术创建受控图案，并在体外评估性能。