NIRT: Ink Jetting of Nanostructured Matrices for Controlled Gene Delivery

摘要-0210238P。Kumta，L.Walker，L.Weiss，P.Campbell和J.HollingerCarnegie Mellon University提出了一种基于改进喷墨打印技术的受控基因传递的新技术，并开发了一种新的组织工程技术。PI试图创建一种仿生细胞外基质，具有受控的纳米CaP的时空模式，其中包含DNA或质粒生长因子。受控图案将利用喷墨技术创建，并将在体外进行性能评估。

ABSTRACTCTS-0210238P. Kumta, L. Walker, L. Weiss, P. Campbell and J. HollingerCarnegie Mellon UniversityA novel techniques based on modification of ink jet printing technology for controlled Gene delivery and development of a new technology for tissue engineering is proposed. The PIs seek to create a biomimetic extracellular matrix with controlled temporal-spatial patterns of NanoCaPs that contains DNAs or plasmid growth factor. The controlled patterns will be created with the ink-jet technology and the performance will be evaluated in-vitro.