SGER: Activated Hydrogen Peroxide Detoxification of Chemical-Biological Warfare Agents

这项研究的目标是由泰伦斯J.柯林斯教授在麦基-梅隆大学，这是由无机，生物无机和有机化合物化学计划的支持，是开发四氨基大环铁（III）配合物（TAML活化剂）与过氧化氢结合，以摧毁化学和生物战剂的污染表面。 这些试剂包括有机磷酸酯神经毒气，例如沙林和VX，芥子气（烷基化）化合物和生物试剂，包括细菌，病毒和毒素。 这项探索性研究小额赠款支持开发广泛适用的净化程序，以消除各种化学和生物战剂，包括已经或可能用于恐怖主义的病毒和细菌，如炭疽。

The objective of this research by Professor Terrence J. Collins at Carnegie-Mellon University, which is supported by the Inorganic, Bioinorganic and Oganometallic Chemistry Program, is to develop tetraamidomacrocyclic iron(III) complexes (TAML activators) in conjunction with hydrogen peroxide to destroy chemical and biological warfare agents on contaminated surfaces. These agents include organophosphorous ester nerve gases such as, such as Sarin and VX, mustard (alkylating) compounds and biological agents including bacteria, virus, and toxins. This Small Grant for Exploratory Research supports the development of a widely-applicable decontaminating process to eliminate various chemical and biological warfare agents including viruses and bacteria, such as anthrax, that have been or may be used in terrorism.