SBIR Phase I: Urea Sensing Biocatalytic Polymers

这个小型企业创新研究(SBIR)第一阶段项目建议开发一种使用酶聚氨酯聚合物的尿素传感器。该产品概念便宜，使用非常方便，不需要额外的分析设备或电力。其配方中使用的酶的严格特异性将使传感器在检测尿素时具有高精度，并应限制假阳性和阴性信号。表面和解决方案的采样只需要一个简单的步骤，从而限制了用户出错的可能性。最后，几分钟左右的快速响应时间将很好地与传感器的目标应用相对应。该项目的商业应用将在与食品服务行业和保健机构相关的监管测试领域。由于洗手间清洁不当可能导致细菌污染，因此在医院卫生间设施中使用尿素检测传感器可能有助于降低患者感染率。

This Small Business Innovation Research (SBIR)Phase Iproject proposes to develop a urea sensor using enzyme polyurethane polymers. The product concept is inexpensive, very easy to use and requires no additional analytical equipment or electricity. The strict specificity of the enzymes used in its formulation will provide the sensor with high precision in detecting urea and should limit false positive and negative signals. Sampling of surfaces and solutions will require only 1 simple step, limiting the potential for user error. Finally, rapid response times, on the order of a few minutes, will correspond well with the target applications of the sensor. The commercial applications of this project will be in the area of regulatory testing linked to the food service industry and health care establishments. Because improper cleaning practices of restrooms can lead to bacterial contamination, the use of urea-detecting sensors in hospital bathroom facilities may aid in reducing patient infection rates.