SBIR Phase II: Nonintrusive Diode Laser Sensor for Bottled Drugs

SBIR 第二阶段：用于瓶装药物的非侵入式二极管激光传感器

• 批准号: 0215797
• 负责人: Mark Paige
• 金额: $ 50万
• 依托单位: Southwest Sciences Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-15 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0215797&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Nonintrusive; Diode

This Small Business Innovation Research (SBIR) Phase II project is designed to develop a nonintrusive diode laser sensor for detecting oxygen in the headspace of pharmaceutical vials. Many drugs are oxygen sensitive and must be bottled in an oxygen free environment. There are no nonintrusivemethods available to measure residual oxygen levels in sealed product vials. A nonintrusive sensor would generate large cost savings for pharmaceutical manufacturers. During the Phase II project, a prototype off-line instrument will be constructed. This instrument will be tested at pharmaceutical manufacturing facilities. In addition if time permits, on-line experimental measurements will be performed.In addition to being useful for the pharmaceutical industry, this technology will be extendable to a variety of packaged products in other industries. These industries include the food, alcoholic beverage, and medical instrument markets. This technology can also be used to detectother species in packaged products such as water vapor or carbon dioxide.

这个小型企业创新研究（SBIR）第二阶段项目旨在开发一种非侵入式二极管激光传感器，用于检测药瓶顶部空间中的氧气。许多药物对氧气敏感，必须在无氧环境中装瓶。没有非侵入性方法可用于测量密封产品小瓶中的残留氧气水平。非侵入式传感器将为制药商节省大量成本。在第二阶段项目期间，将建造一个原型离线仪器。该仪器将在制药厂进行检测。此外，如果时间允许，还将进行在线实验测量。除了对制药行业有用外，这项技术还将扩展到其他行业的各种包装产品。这些行业包括食品、酒精饮料和医疗器械市场。该技术还可用于检测包装产品中的其他物质，如水蒸气或二氧化碳。