SBIR Phase II: Zero Trust Solution for Precision Medicine and Precision Health Data Exchanges

SBIR 第二阶段：精准医疗和精准健康数据交换的零信任解决方案

• 批准号: 2226026
• 负责人: Anthony Deasey
• 金额: $ 98.49万
• 依托单位: SOFTHREAD, INC.
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-04-01 至 2026-03-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2226026&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Zero; Trust

This Small Business Innovation Research (SBIR) Phase II project leverages novel converging technologies and expands blockchain technology to new healthcare domains enabling the secure exchange of confidential, precision health information such as advanced directives and life-sustaining management within and between organizations. The confidentiality, security, and efficiency of data management are critically important in advanced care and life-sustaining treatment decision pathways for ethical, clinical, regulatory, and legal reasons. The combination of the proprietary blockchain solution with artificial intelligence (AI) capabilities and edge computing enablement offers enhanced privacy and security, improved audit-readiness, better risk management, and superior operational efficiency. The solution functions as an overlay to legacy systems. It easily integrates with existing information management systems, in the cloud or on premise. Further, this solution is scalable, providing a competitive advantage and ease of adoption for stakeholders, including those who are seeking Web 3.0 upward compatibility. In addition to the direct impact within this application area, the technology can have a broader positive influence on the economy and society by preventing or reducing data breaches, increasing trust and quality of life, and reducing the total cost of healthcare. This SBIR Phase II project establishes a novel, efficient, and effective solution for advanced directives and life-sustaining management, which is one of the critical areas within precision health and medicine given the highly personalized and ethically-complex nature of the application. The zero-trust solution achieves decentralized confidentiality, fine-grained access control, and robust intrusion tolerance by avoiding any single point of failure and maintaining operational efficiency. By leveraging modern cryptographic protocols, pre-built privacy-preserving smart contracts, advanced user access control overlays, support for publish/subscribe messaging patterns, integration with off-chain operations, and confidentiality-preserving machine learning models, the solution offers a unique, modular, decentralized architecture that can meet complex regulatory, privacy and security requirements. Further, the technology is specifically designed to address Internet of Things (IoT) network security and data management at scale. The project aims to reduce cyber-vulnerability, increase operational flexibility and achieve scalability that will prove beneficial to a broad array of related healthcare and precision medicine domains such as transplant services, genomic medicine, or biobanks where data confidentiality is of critical importance, especially as these are highly vulnerable to data breaches and cyberattacks.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）II期项目利用新颖的融合技术，并将区块链技术扩展到新的医疗保健领域，从而可以安全地交换机密，精确的健康信息，例如高级指令和组织之间和维持生命的管理。数据管理的机密性，安全性和效率在道德，临床，监管和法律原因的先进护理和维持生命的治疗决策途径中至关重要。专有区块链解决方案与人工智能（AI）功能和边缘计算启用的组合提供了增强的隐私和安全性，改善的审计准备，更好的风险管理以及出色的运营效率。该解决方案用作传统系统的覆盖层。它可以轻松地与现有信息管理系统，云或前提集成。此外，该解决方案是可扩展的，为利益相关者（包括寻求Web 3.0向上兼容性的人）提供了竞争优势和易用性。 除了该应用领域内的直接影响外，该技术还可以通过预防或减少数据泄露，提高信任和生活质量并降低医疗保健的总成本来对经济和社会产生更大的积极影响。这个SBIR II期项目为高级指令和维持生命的管理建立了一种新颖，高效且有效的解决方案，鉴于应用程序的高度个性化和道德化的性质，这是精确健康和医学中的关键领域之一。零信托解决方案通过避免任何单个失败并维持操作效率来实现分散的机密性，细粒度的访问控制和稳健的入侵耐受性。通过利用现代加密协议，预先构建的隐私合同，高级用户访问控制叠加层，支持/订阅消息传递模式的支持，与链链操作的积分以及保密性的机器学习模型，该解决方案可以提供独特的，模块化的，分散的架构，可以满足复杂的法规，隐私，隐私，隐私，保密和安全要求。此外，该技术是专门设计的，旨在按大规模解决物联网（IoT）网络安全和数据管理。该项目旨在降低网络可耗尽性，提高运行灵活性并实现可伸缩性，这将被证明有益于广泛的相关医疗保健和精确医学领域，例如移植服务，基因组医学或生物库，数据保密性具有重要的重要性，尤其是在这些数据中非常容易通过数据违反和Cyber​​attack的奖励。利用基金会的知识分子和更广泛的影响审查标准。